Sugi Predict

Sugi Predict / Compounds / SCHEMBL18563264

SCHEMBL18563264

SCHEMBL18563264

c1ccc2c(c1)Oc1ccc(N(c3ccc4c(c3)Oc3ccccc3O4)c3ccc4c(c3)Oc3ccccc3O4)cc1O2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AHR P35869 9/20 0.52
▸ NPC1 O15118 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ MAOA P21397 2/20 0.36
▸ MAOB P27338 2/20 0.36
▸ ALOX5 P09917 1/20 0.36
▸ KDM4E B2RXH2 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ MAPT P10636 2/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18563199 0.94 AHR (0.47) AHRNPC1LMNARAB9ASMN1; SMN2
SCHEMBL18563297 0.94 AHR (0.47) AHRNPC1LMNARAB9ASMN1; SMN2
SCHEMBL22180111 0.91 ALDH1A1 (0.46) AHRNPC1LMNARAB9ASMN1; SMN2
SCHEMBL22825386 0.90 AHR (0.44) AHRNPC1LMNARAB9ASMN1; SMN2
SCHEMBL18563290 0.88 AHR (0.42) AHRALOX5KDM4EALDH1A1MAPT
SCHEMBL18563227 0.88 AHR (0.42) AHRALOX5KDM4EALDH1A1MAPT
SCHEMBL18563259 0.88 AHR (0.42) AHRALOX5KDM4EALDH1A1MAPT
SCHEMBL18563248 0.87 AHR (0.41) AHRALOX5KDM4EALDH1A1MAPT
SCHEMBL12259278 0.82 AHR (0.37) AHRMAOAKDM4EALDH1A1MAPT
SCHEMBL24277620 0.82 KDM4E (0.43) AHRKDM4EALDH1A1MAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10361373-B2 Condensed-cyclic compound and organic light emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-23 — — US disclosed
US-20170062720-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-02 — — US disclosed
US-20170062720-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-02 — — US disclosed
EP-3135673-A2 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME Samsung Display Co., Ltd. (KR) 2017-03-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170062720-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LRRK2, SLC18A1, CCNT1 AHR 2829/4885NPC1 1232/4885LMNA 1950/4885
US-10361373-B2 Condensed-cyclic compound and organic light emitting device comprising the same LRRK2, SLC18A1, CCNT1 AHR 2829/4885NPC1 1232/4885LMNA 1950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.