Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18568884 | 0.84 | — | — | |
| SCHEMBL18568724 | 0.83 | SMN1; SMN2 (0.40) | METAP1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18568895 | 0.82 | CCR4 (0.33) | ALDH1A1 | |
| SCHEMBL18568875 | 0.81 | — | — | |
| SCHEMBL18568847 | 0.81 | — | — | |
| SCHEMBL18569083 | 0.81 | RAB9A (0.41) | ROCK2RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18568949 | 0.80 | SRC (0.31) | RAB9ANPC1ALDH1A1SMN1; SMN2SYK | |
| SCHEMBL18568727 | 0.80 | — | — | |
| SCHEMBL18568917 | 0.80 | NUDT1 (0.33) | RAB9ANPC1ALDH1A1SMN1; SMN2SYK | |
| SCHEMBL12783283 | 0.79 | METAP1 (0.37) | METAP1ROCK2RAB9ACFTRSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308839-B1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICALS CO (JP) | 2017-03-01 | — | — | EP | disclosed |