Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.32 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290519 | 0.88 | DYRK1A (0.39) | PIK3CGDYRK1ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL18569306 | 0.88 | PIK3CG (0.37) | PIK3CGDYRK1AXIAPBIRC2PTGDR2 | |
| SCHEMBL13047720 | 0.88 | DYRK1A (0.43) | PIK3CGDYRK1ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17488375 | 0.87 | GAA (0.37) | DYRK1ACYP1A2CYP3A4CYP2C19PTGES | |
| SCHEMBL13047738 | 0.86 | LIPG (0.37) | PIK3CGDYRK1ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13047732 | 0.85 | PIK3CG (0.35) | PIK3CGDYRK1ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13074916 | 0.85 | PIK3CG (0.35) | PIK3CGDYRK1ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13074535 | 0.85 | LIPG (0.36) | PIK3CGDYRK1ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL18569322 | 0.83 | CYP1A2 (0.38) | PIK3CGDYRK1ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL25405384 | 0.82 | PIK3CG (0.44) | PIK3CGDYRK1ACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614826-B1 | Process for preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |