SCHEMBL290519

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13075003	0.90	DYRK1A (0.39)	DYRK1APIK3CGCYP1A2CYP3A4CYP2C19
	SCHEMBL13074543	0.90	DYRK1A (0.39)	DYRK1APIK3CGXIAPBIRC2PTGDR2
	SCHEMBL290684	0.89	PIK3CG (0.36)	DYRK1APIK3CGCYP1A2CYP3A4CYP2C19
	SCHEMBL13048428	0.88	DYRK1A (0.38)	DYRK1APIK3CGXIAPBIRC2PTGDR2
	SCHEMBL13048214	0.88	DYRK1A (0.38)	DYRK1APIK3CGXIAPBIRC2PTGDR2
	SCHEMBL18568993	0.88	PIK3CG (0.38)	DYRK1APIK3CGCYP1A2CYP3A4CYP2C19
	SCHEMBL13047936	0.87	XIAP (0.34)	DYRK1APIK3CGCYP1A2CYP3A4CYP2C19
	SCHEMBL3744092	0.87	KMT2A (0.36)	DYRK1ACYP1A2CYP3A4CYP2C19PTGES
	SCHEMBL13047720	0.87	DYRK1A (0.43)	DYRK1APIK3CGCYP1A2CYP3A4CYP2C19
	SCHEMBL18569317	0.86	DYRK1A (0.37)	DYRK1ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.