Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122697 | 0.86 | OPRM1 (0.52) | OPRM1CA1SPHK1LMNATP53 | |
| SCHEMBL22471943 | 0.83 | OPRM1 (0.50) | OPRM1ACE2SPHK1LMNATP53 | |
| SCHEMBL16779862 | 0.83 | OPRM1 (0.50) | OPRM1ACE2SPHK1LMNATP53 | |
| SCHEMBL4654330 | 0.77 | DNM1 (0.43) | OPRM1CA1LMNADNM1TSHR | |
| SCHEMBL14778098 | 0.77 | OPRM1 (0.44) | OPRM1ACE2SPHK1LMNADNM1 | |
| SCHEMBL20921658 | 0.77 | OPRM1 (0.35) | OPRM1CA1SPHK1ADH1BADH1C | |
| SCHEMBL2185803 | 0.76 | OPRM1 (0.48) | OPRM1ACE2CA1SPHK1LMNA | |
| SCHEMBL1028502 | 0.76 | OPRM1 (0.48) | OPRM1ACE2CA1SPHK1LMNA | |
| SCHEMBL25220046 | 0.75 | SPHK1 (0.50) | OPRM1ACE2SPHK1LMNATP53 | |
| SCHEMBL25350097 | 0.75 | SPHK1 (0.50) | OPRM1ACE2SPHK1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882740-B1 | IAP ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2017-03-01 | — | — | EP | disclosed |