Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249636 | 0.83 | PTPN1 (0.47) | PTPN1TAAR1TDP1SLC6A2SLC6A4 | |
| SCHEMBL28291937 | 0.77 | PTPN1 (0.47) | PTPN1TDP1TP53KDM4E | |
| SCHEMBL28924349 | 0.74 | PTPN1 (0.48) | PTPN1TDP1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL28339089 | 0.74 | TDP1 (0.45) | PTPN1TAAR1TDP1AOC3ALDH1A1 | |
| SCHEMBL3864995 | 0.73 | MEN1 (0.46) | PTPN1TAAR1TDP1ALDH1A1GAA | |
| SCHEMBL31203 | 0.72 | TDP1 (0.55) | PTPN1TAAR1TDP1ALDH1A1TSHR | |
| SCHEMBL29534868 | 0.72 | TDP1 (0.55) | PTPN1TAAR1TDP1ALDH1A1TSHR | |
| SCHEMBL8676051 | 0.72 | GAA (0.39) | PTPN1SLC6A2SLC6A4ALDH1A1TSHR | |
| SCHEMBL8966732 | 0.72 | PTPN1 (0.44) | PTPN1TDP1SMN1; SMN2HTR1A | |
| SCHEMBL14135416 | 0.72 | PTPN1 (0.45) | PTPN1TAAR1AOC3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1632477-B1 | BENZAMIDE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2017-03-01 | — | — | EP | disclosed |