Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3864995 | 0.82 | MEN1 (0.46) | PTPN1TDP1MEN1PABPC1KMT2A | |
| SCHEMBL4495007 | 0.76 | PTPN1 (0.41) | PTPN1TDP1MEN1PABPC1KMT2A | |
| SCHEMBL249636 | 0.75 | PTPN1 (0.47) | PTPN1TDP1SMN1; SMN2 | |
| SCHEMBL15573965 | 0.74 | PTPN1 (0.40) | PTPN1TDP1MEN1PABPC1KMT2A | |
| SCHEMBL28431237 | 0.73 | HTT (0.44) | PTPN1TDP1MEN1PABPC1KMT2A | |
| SCHEMBL31203 | 0.72 | TDP1 (0.55) | PTPN1TDP1 | |
| SCHEMBL29534868 | 0.72 | TDP1 (0.55) | PTPN1TDP1 | |
| SCHEMBL18569445 | 0.72 | PTPN1 (0.45) | PTPN1TDP1HTR1ASMN1; SMN2 | |
| SCHEMBL17374923 | 0.72 | PTPN1 (0.48) | PTPN1TDP1MEN1PABPC1KMT2A | |
| SCHEMBL28924349 | 0.71 | PTPN1 (0.48) | PTPN1TDP1MEN1PABPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601406-B1 | Method for the preparation of (5-amino-2-(2-hydroxyethylamino)phenyl)(2-hydroxyethyl) sulphone | BAYER AG (DE) | 1996-02-28 | — | — | EP | claimed |
| US-5414131-A | Process for preparing [5-amino-2-(2-hydroxyethylamino)-phenyl](2-hydroxyethyl)sulphone | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | claimed |
| JP-6199772-A | — | — | None | — | — | JP | disclosed |
| US-5414131-A | Process for preparing [5-amino-2-(2-hydroxyethylamino)-phenyl](2-hydroxyethyl)sulphone | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |
| JP-H06199772-A | PREPARATION OF (5-AMINO-2-(2-HYDROXY-ETHYLAMINO)-PHENYL)(2-HYDROXYETHYL)SULPHONE | BAYER AG | 1994-07-19 | — | — | JP | disclosed |