Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.50 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | CTSG | P08311 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16402963 | 1.00 | ELANE (0.50) | ELANEF2CTSGNPC1RAB9A | |
| SCHEMBL16403228 | 0.91 | HCRTR2 (0.45) | ELANENPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL18569885 | 0.91 | HCRTR2 (0.45) | ELANENPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL30054873 | 0.91 | HCRTR2 (0.45) | ELANENPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL3402980 | 0.86 | ALDH1A1 (0.44) | ELANEF2CTSGHCRTR2 | |
| SCHEMBL115758 | 0.86 | ALDH1A1 (0.44) | ELANEF2CTSGHCRTR2 | |
| SCHEMBL20446568 | 0.82 | AGTR2 (0.47) | NPC1RAB9ASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL17755338 | 0.82 | AGTR2 (0.47) | NPC1RAB9ASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL5765292 | 0.82 | AGTR2 (0.47) | NPC1RAB9ASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL6941068 | 0.82 | AGTR2 (0.47) | NPC1RAB9ASMN1; SMN2TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004084-B1 | SUBSTITUTED BENZOXAZOLES | Bayer Pharma AG (DE) | 2017-03-01 | — | — | EP | disclosed |