SCHEMBL1856965

SCHEMBL1856965

COc1cccc(-c2ccc([N+]#N)c(OC)c2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.48
CYP1A1 P04798 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2E1 P05181 2/20 0.47
CYP3A4 P08684 2/20 0.47
CYP2C8 P10632 2/20 0.47
CYP2D6 P10635 2/20 0.47
CYP2A6 P11509 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP4B1 P13584 2/20 0.47
CYP2B6 P20813 2/20 0.47
CYP3A5 P20815 2/20 0.47
CYP2A7 P20853 2/20 0.47
CYP3A7 P24462 2/20 0.47
CYP2F1 P24903 2/20 0.47
CYP2C18 P33260 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP2J2 P51589 2/20 0.47
CYP4F2 P78329 2/20 0.47
CYP4F8 P98187 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL5574410 0.90 ERN1 (0.47) ERN1CYP1A1CYP1A2CYP2E1CYP3A4
SCHEMBL1856962 0.88 ALDH1A1 (0.48) ERN1CYP3A4PDGFRBPDGFRADYRK1A
SCHEMBL5572801 0.86 ALDH1A1 (0.47) ERN1CYP3A4PDGFRBPDGFRADYRK1A
Hydrochloric Acid SCHEMBL9816483 0.86 ALDH1A1 (0.47) ERN1CYP3A4PDGFRBPDGFRADYRK1A
Hydrochloric Acid SCHEMBL5384716 0.86 ALDH1A1 (0.47) ERN1CYP3A4PDGFRBPDGFRADYRK1A
Hydrochloric Acid SCHEMBL11080769 0.85 NPC1 (0.44) CYP3A4
Hydrochloric Acid SCHEMBL5444051 0.84 ALDH1A1 (0.45) ERN1CYP3A4PDGFRBPDGFRADYRK1A
SCHEMBL8497623 0.82 CA1 (0.56) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8
Hydrochloric Acid SCHEMBL3804779 0.81 CYP1A1 (0.54) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8
Hydrochloric Acid SCHEMBL8498491 0.80 CA1 (0.54) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7846383-B2 Lateral flow assay device and absorbent article containing same KIMBERLY-CLARK WORLDWIDE, INC. (US) 2010-12-07 US claimed
US-20080145945-A1 Lateral flow assay device and absorbent article containing same KIMBERLY-CLARK WORLDWIDE, INC. 2008-06-19 US claimed
US-7935538-B2 Indicator immobilization on assay devices KIMBERLY-CLARK WORLDWIDE, INC. (US) 2011-05-03 US disclosed
US-7846383-B2 Lateral flow assay device and absorbent article containing same KIMBERLY-CLARK WORLDWIDE, INC. (US) 2010-12-07 US disclosed
EP-2092332-A1 INDICATOR IMMOBILIZATION ON ASSAY DEVICES Kimberly-Clark Worldwide, Inc. (US) 2009-08-26 EP disclosed
EP-1271143-B1 Test strip having a porous filter layer ARKRAY INC (JP) 2009-05-06 EP disclosed
WO-2008075216-A1 INDICATOR IMMOBILIZATION ON ASSAY DEVICES KIMBERLY-CLARK WORLDWIDE, INC. (US) 2008-06-26 WO disclosed
US-20080145949-A1 Indicator immobilization on assay devices KIMBERLY-CLARK WORLDWIDE, INC. 2008-06-19 US disclosed
US-20080145945-A1 Lateral flow assay device and absorbent article containing same KIMBERLY-CLARK WORLDWIDE, INC. 2008-06-19 US disclosed
US-7201871-B2 Specimen having capability of separating solid component ARKRAY INC. (JP) 2007-04-10 US disclosed
US-7189576-B2 Method for measuring substance and testing piece ARKRAY INC. (JP) 2007-03-13 US disclosed
US-20030203503-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-10-30 US disclosed
US-20030180183-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-25 US disclosed
US-20030175985-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-18 US disclosed
US-20030175984-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-18 US disclosed
US-20030166295-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-04 US disclosed
US-20030044316-A1 Specimen having capability of separating solid component ARKRAY INC. (JP) 2003-03-06 US disclosed
EP-1271143-A1 SPECIMEN HAVING CAPABILITY OF SEPARATING SOLID COMPONENT ARKRAY, Inc. (JP) 2003-01-02 EP disclosed
EP-0860695-A9 METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) 2001-10-17 EP disclosed
EP-0860695-A1 METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) 1998-08-26 EP disclosed