Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5384716

COc1cc(-c2ccc([N+]#N)c(OC)c2)ccc1[N+]#N.[Cl-].[Cl-]

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
HSD17B10 Q99714 3/20 0.47
CYP3A4 P08684 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
TSHR P16473 1/20 0.47
HPGD P15428 3/20 0.39
PDE4A P27815 1/20 0.38
DYRK1A Q13627 1/20 0.38
LMNA P02545 1/20 0.36
KDM4E B2RXH2 2/20 0.35
MAPK1 P28482 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
PDGFRB P09619 1/20 0.35
PDGFRA P16234 1/20 0.35
HTT P42858 1/20 0.35
ERN1 O75460 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5444051 0.98 ALDH1A1 (0.45) ALDH1A1HSD17B10CYP3A4TDP1TSHR
SCHEMBL1856962 0.98 ALDH1A1 (0.48) ALDH1A1HSD17B10CYP3A4TDP1TSHR
Hydrochloric Acid SCHEMBL9816483 0.96 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP3A4TDP1TSHR
SCHEMBL5572801 0.96 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP3A4TDP1TSHR
Zinc Chloride SCHEMBL29375627 0.93 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP3A4TDP1TSHR
Hydrochloric Acid SCHEMBL11080769 0.91 NPC1 (0.44) ALDH1A1HSD17B10CYP3A4TDP1TSHR
SCHEMBL14487132 0.89 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP3A4TDP1TSHR
SCHEMBL12364590 0.87 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP3A4TDP1TSHR
SCHEMBL1856965 0.86 ERN1 (0.48) CYP3A4DYRK1APDGFRBPDGFRAERN1
Hydrochloric Acid SCHEMBL8498491 0.82 CA1 (0.54) ALDH1A1CYP3A4HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12613218-B2 Devices and methods for selective detection of cannabinoids UNIVERSITY OF OTTAWA (CA) 2026-04-28 US claimed
EP-3969890-B1 METHODS FOR SELECTIVE DETECTION OF CANNABINOIDS UNIV OTTAWA (CA) 2026-01-28 EP claimed
US-20220221422-A1 DEVICES AND METHODS FOR SELECTIVE DETECTION OF CANNABINOIDS UNIVERSITY OF OTTAWA (CA) 2022-07-14 US claimed
EP-3969890-A1 DEVICES AND METHODS FOR SELECTIVE DETECTION OF CANNABINOIDS University of Ottawa (CA) 2022-03-23 EP claimed
WO-2020232532-A1 DEVICES AND METHODS FOR SELECTIVE DETECTION OF CANNABINOIDS UNIVERSITY OF OTTAWA (CA) 2020-11-26 WO claimed
US-9759733-B1 Mass produced, low cost, portable test kit for the detection and identification of narcotics VERITEQUE USA, INC. 2017-09-12 US claimed
US-7229668-B2 Process for the electrochemical production of a carbon-containing material whose surface is modified with organic groups, and use of the modified material CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2007-06-12 US claimed
US-3930951-A 4,4'-BI(2-METHOXYBENZENE DIAZONIUM CHLORIDE) CORNING GLASS WORKS (US) 1976-01-06 US claimed
US-12613218-B2 Devices and methods for selective detection of cannabinoids UNIVERSITY OF OTTAWA (CA) 2026-04-28 US disclosed
EP-3969890-B1 METHODS FOR SELECTIVE DETECTION OF CANNABINOIDS UNIV OTTAWA (CA) 2026-01-28 EP disclosed
US-20220221422-A1 DEVICES AND METHODS FOR SELECTIVE DETECTION OF CANNABINOIDS UNIVERSITY OF OTTAWA (CA) 2022-07-14 US disclosed
EP-3969890-A1 DEVICES AND METHODS FOR SELECTIVE DETECTION OF CANNABINOIDS University of Ottawa (CA) 2022-03-23 EP disclosed
WO-2020232532-A1 DEVICES AND METHODS FOR SELECTIVE DETECTION OF CANNABINOIDS UNIVERSITY OF OTTAWA (CA) 2020-11-26 WO disclosed
US-9759733-B1 Mass produced, low cost, portable test kit for the detection and identification of narcotics VERITEQUE USA, INC. 2017-09-12 US disclosed
US-20020144912-A1 Process for the electrochemical production of a carbon-containing material whose surface is modified with organic groups, and use of the modified material CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) 2002-10-10 US disclosed
US-6435240-B1 Process for the electrochemical production of a carbon-containing material whose surface is modified with organic groups, and use of the modified material CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2002-08-20 US disclosed
EP-0132313-B1 REAGENTS, TEST KITS AND METHODS FOR THE DETECTION OF CANNABINOIDS EREZ FORENSIC TECHNOLOGY LTD. (IL) 1991-09-18 EP disclosed
US-4342833-A CHEMICALLY BONDED TO CYA OGEN BROMIDE ACTIVATED AGAROSE BETHESDA RESEARCH LABORATORY (US) 1982-08-03 US disclosed
US-3930951-A 4,4'-BI(2-METHOXYBENZENE DIAZONIUM CHLORIDE) CORNING GLASS WORKS (US) 1976-01-06 US disclosed
US-3930951-A 4,4'-BI(2-METHOXYBENZENE DIAZONIUM CHLORIDE) CORNING GLASS WORKS (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12613218-B2 Devices and methods for selective detection of cannabinoids NCS1, TMCO1, CNR2 ALDH1A1 3073/4885HSD17B10 3970/4885CYP3A4 3157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.