Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16399764 | 1.00 | BRD4 (0.41) | BRD4ELANEHSD11B1ALDH1A1MAPT | |
| SCHEMBL16400195 | 0.85 | ELANE (0.40) | BRD4ELANEHSD11B1ALDH1A1MAPT | |
| SCHEMBL16399520 | 0.84 | ELANE (0.37) | BRD4ELANEHSD11B1ALDH1A1MAPT | |
| SCHEMBL16399773 | 0.83 | BRD4 (0.40) | BRD4ELANEHSD11B1ALDH1A1MAPT | |
| SCHEMBL16400119 | 0.82 | ELANE (0.39) | BRD4ELANEHSD11B1ALDH1A1MAPT | |
| SCHEMBL16399366 | 0.82 | HSD11B1 (0.40) | BRD4ELANEHSD11B1ALDH1A1MAPT | |
| SCHEMBL16399349 | 0.81 | ELANE (0.38) | BRD4ELANEHSD11B1ALDH1A1MAPT | |
| SCHEMBL16400657 | 0.79 | HSD11B1 (0.35) | BRD4ELANEHSD11B1ALDH1A1MAPT | |
| SCHEMBL17685931 | 0.78 | SMYD2 (0.36) | ELANEHSD11B1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL16399447 | 0.74 | AMPD2 (0.44) | ELANEALDH1A1MAPTHSD17B10CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004084-B1 | SUBSTITUTED BENZOXAZOLES | Bayer Pharma AG (DE) | 2017-03-01 | — | — | EP | disclosed |