SCHEMBL18570565

SCHEMBL18570565

Cc1cc(NCCCN(C)C)ccc1N

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
DRD3 P35462 1/20 0.46
CYP3A4 P08684 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
THRB P10828 1/20 0.42
ALOX15 P16050 1/20 0.42
RECQL P46063 1/20 0.42
HIF1A Q16665 1/20 0.42
S100B P04271 1/20 0.41
KDM4E B2RXH2 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
BRD4 O60885 2/20 0.39
ATAD2 Q6PL18 2/20 0.39
MAP4K4 O95819 1/20 0.39
HTT P42858 1/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
SLC2A1 P11166 1/20 0.38
APOBEC3A P31941 1/20 0.38
RAD52 P43351 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18393155 0.87 DRD3 (0.48) ALDH1A1DRD3KDM4EL3MBTL1MAP4K4
SCHEMBL18570642 0.86 ALDH1A1 (0.45) ALDH1A1DRD3CYP3A4TDP1THRB
SCHEMBL6376391 0.86 ALDH1A1 (0.53) ALDH1A1CYP3A4TDP1THRBALOX15
SCHEMBL2933227 0.86 ALDH1A1 (0.58) ALDH1A1CYP3A4TDP1THRBALOX15
SCHEMBL18570563 0.85 ALDH1A1 (0.44) ALDH1A1DRD3CYP3A4TDP1THRB
Hydrochloric Acid SCHEMBL4952474 0.84 ALDH1A1 (0.51) ALDH1A1CYP3A4TDP1THRBALOX15
SCHEMBL6369975 0.84 ALDH1A1 (0.56) ALDH1A1CYP3A4TDP1THRBALOX15
SCHEMBL6369929 0.84 ALDH1A1 (0.56) ALDH1A1CYP3A4TDP1THRBALOX15
SCHEMBL14419461 0.84 ALDH1A1 (0.46) ALDH1A1CYP3A4TDP1THRBALOX15
SCHEMBL4858416 0.83 ALDH1A1 (0.65) ALDH1A1CYP3A4TDP1THRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2734179-B1 NOVEL OXIDATION DYE PRECURSORS HENKEL AG & CO KGAA (DE) 2017-03-01 EP disclosed