Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | S100B | P04271 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6369975 | 0.98 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL6369929 | 0.98 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| Hydrochloric Acid SCHEMBL4954707 | 0.96 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| Hydrochloric Acid SCHEMBL4949443 | 0.96 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL6376391 | 0.96 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| Hydrochloric Acid SCHEMBL4952474 | 0.94 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL2126641 | 0.92 | CYP3A4 (0.53) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL205604 | 0.91 | ABL1 (0.56) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL4863422 | 0.91 | ALDH1A1 (0.73) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL10406890 | 0.91 | ABL1 (0.56) | ALDH1A1CYP3A4TDP1THRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739084-B1 | Double para-phenylenediamines joined by a linker comprising a saturated cyclic radical and use thereof as dyeing agents | OREAL (FR) | 2010-09-15 | — | — | EP | disclosed |
| US-7422609-B2 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | L'OREAL S.A. (FR) | 2008-09-09 | — | — | US | disclosed |
| US-7413580-B2 | Double para-phenylenediamines joined by a linker arm substituted with one or more carboxylic radicals and/or derivatives and use in dyeing | L'OREAL S.A. (FR) | 2008-08-19 | — | — | US | disclosed |
| EP-1739074-B1 | Novel double para-phenylenediamines joined by a branched aliphatic group and use in dyeing | OREAL (FR) | 2008-03-12 | — | — | EP | disclosed |
| US-20070011825-A1 | Novel double para-phenylenediamines joined by a linkage comprising a saturated cyclic radical and use in dyeing | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011828-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and method of dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011827-A1 | Novel double para-phenylenediamines joined by a linker arm substituted with at least one group chosen from hydroxyl, alkoxy, and/or amino groups and method of dyeing keratinous fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011824-A1 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011829-A1 | Novel double para-phenylenediamines joined by a linkage comprising an atom chosen from sulphur and nitrogen and method for dyeing keratinous fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011826-A1 | Novel double para-phenylenediamines joined by a linker arm substituted with one or more carboxylic radicals and/or derivatives and use in dyeing | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1739074-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739085-A1 | Cosmetic composition containing a double para-phenylenediamines joined by an aromatic group and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739079-A1 | Novel bis-para-phenylendiamins joined by a linker arm comprising a sulphur or nitrogen atom and their use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739076-A1 | Novel BIS para-phenylenediamines joined by a linker arm substituted with one or more carboxylic radicals and/or derivatives and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739084-A1 | Double para-phenylenediamines joined by a linker comprising a saturated cyclic radical and use thereof as dyeing agents | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739075-A1 | Novel double para-phenylenediamines joined by a linker arm substituted with one or more hydroxyl, alkoxy and/or amino groups and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011828-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and method of dyeing keratin fibers | KRT18, CDC73, DSP | ALDH1A1 976/4885CYP3A4 3719/4885TDP1 2217/4885 |
| US-20070011829-A1 | Novel double para-phenylenediamines joined by a linkage comprising an atom chosen from sulphur and nitrogen and method for dyeing keratinous fibers | KRT18, DSP, CDC73 | ALDH1A1 798/4885CYP3A4 3949/4885TDP1 2060/4885 |
| US-20070011824-A1 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | KRT18, CDC73, JUP | ALDH1A1 127/4885CYP3A4 1046/4885TDP1 1242/4885 |
| US-20070011826-A1 | Novel double para-phenylenediamines joined by a linker arm substituted with one or more carboxylic radicals and/or derivatives and use in dyeing | KRT18, DSP, CDC73 | ALDH1A1 405/4885CYP3A4 3230/4885TDP1 1819/4885 |
| US-20070011827-A1 | Novel double para-phenylenediamines joined by a linker arm substituted with at least one group chosen from hydroxyl, alkoxy, and/or amino groups and method of dyeing keratinous fibers | KRT18, PLOD3, DSP | ALDH1A1 298/4885CYP3A4 2964/4885TDP1 1183/4885 |
| US-20070011825-A1 | Novel double para-phenylenediamines joined by a linkage comprising a saturated cyclic radical and use in dyeing | KRT18, CDC73, AOC1 | ALDH1A1 977/4885CYP3A4 3551/4885TDP1 1606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.