Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1489813 | 0.84 | HPGD (0.32) | ALDH1A1TSHRATM | |
| SCHEMBL4860858 | 0.79 | KDM4E (0.31) | — | |
| SCHEMBL9058098 | 0.79 | FAAH (0.30) | — | |
| SCHEMBL11963780 | 0.73 | TSHR (0.35) | ALDH1A1TSHR | |
| SCHEMBL589664 | 0.73 | TSHR (0.35) | ALDH1A1TSHR | |
| SCHEMBL1276105 | 0.73 | MEN1 (0.31) | ALDH1A1 | |
| SCHEMBL4860149 | 0.72 | TDP1 (0.31) | — | |
| SCHEMBL15710709 | 0.72 | TDP1 (0.31) | — | |
| SCHEMBL7160453 | 0.71 | NPC1 (0.32) | ALDH1A1 | |
| SCHEMBL11691480 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10718960-B2 | Method for producing contact lenses with wearing comfort | ALCON INC. (CH) | 2020-07-21 | — | — | US | disclosed |
| EP-3532276-A1 | METHOD FOR PRODUCING SURFACE COATED CONTACT LENSES WITH WEARING COMFORT | Novartis AG (CH) | 2019-09-04 | — | — | EP | disclosed |
| EP-3344447-A1 | METHOD FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON | Novartis AG (CH) | 2018-07-11 | — | — | EP | disclosed |
| US-20180120590-A1 | METHOD FOR PRODUCING CONTACT LENSES WITH WEARING COMFORT | ALCON INC. (CH) | 2018-05-03 | — | — | US | disclosed |
| US-9810812-B2 | Method for producing contact lenses with durable lubricious coatings thereon | NOVARTIS AG (CH) | 2017-11-07 | — | — | US | disclosed |
| US-20170068019-A1 | METHOD FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON | ALCON INC. (CH) | 2017-03-09 | — | — | US | disclosed |