SCHEMBL589664

SCHEMBL589664

C=CCNC=C(C)C(N)=O

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.33
FAAH O00519 1/20 0.32
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11963780 1.00 TSHR (0.35) TSHRALDH1A1TDP1SMN1; SMN2MAPT
SCHEMBL821284 0.81 TSHR (0.34) TSHRALDH1A1TDP1SMN1; SMN2MAPT
SCHEMBL561780 0.81 TSHR (0.34) TSHRALDH1A1TDP1SMN1; SMN2MAPT
SCHEMBL5607925 0.78 ALDH1A1 (0.38) TSHRALDH1A1SMN1; SMN2MAPTFAAH
SCHEMBL27611562 0.76 TSHR (0.33) TSHRALDH1A1SMN1; SMN2MAPTFAAH
SCHEMBL12006818 0.76 TSHR (0.31) TSHRSMN1; SMN2MAPTFAAH
SCHEMBL22818510 0.76 ALDH1A1 (0.30) TSHRALDH1A1
SCHEMBL476570 0.76
SCHEMBL27476590 0.74 TDP1 (0.40) TDP1
SCHEMBL9320741 0.73 TSHR (0.34) TSHRALDH1A1SMN1; SMN2MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11666514-B2 Fibrous structures containing polymer matrix particles with perfume ingredients THE PROCTER & GAMBLE COMPANY (US) 2023-06-06 US claimed
US-20210069111-A1 CATIONIC BLOCK POLYMER MICELLES FOR DELIVERY OF BIOLOGICAL AGENTS REGENTS OF THE UNIVERSITY OF MINNESOTA 2021-03-11 US claimed
US-20200093710-A1 FIBROUS STRUCTURES CONTAINING POLYMER MATRIX PARTICLES WITH PERFUME INGREDIENTS THE PROCTER & GAMBLE COMPANY 2020-03-26 US claimed
EP-1636168-B1 METHOD FOR CONTINUOUSLY PRODUCING ALKYLAMINO(METH)ACRYLAMIDES EVONIK ROEHM GMBH (DE) 2014-03-19 EP claimed
US-7586004-B2 Method for continuously producing alkylamino(meth)acrylamides ROEHM GMBH & CO. KG (DE) 2009-09-08 US claimed
US-20070149811-A1 Method for continuously producing alkylamino(meth)acrylamides ROEHM GMBH & CO. KG (DE) 2007-06-28 US claimed
EP-1636168-A1 METHOD FOR CONTINUOUSLY PRODUCING ALKYLAMINO(METH)ACRYLAMIDES Röhm GmbH & Co. KG (DE) 2006-03-22 EP claimed
WO-2004103952-A1 METHOD FOR CONTINUOUSLY PRODUCING ALKYLAMINO(METH)ACRYLAMIDES Röhm GmbH & Co. KG (DE) 2004-12-02 WO claimed
EP-1330502-B1 COATING COMPOSITION VALSPAR SOURCING INC (US) 2004-06-02 EP claimed
EP-4395730-A1 DISSOLVABLE SOLID STRUCTURE COMPRISING FIRST AND SECOND POLYMERIC STRUCTURANTS The Procter & Gamble Company (US) 2024-07-10 EP disclosed
US-12029799-B2 Conditioning hair care compositions in the form of dissolvable solid structures THE PROCTER & GAMBLE COMPANY (US) 2024-07-09 US disclosed
EP-4380537-A1 WATER INSOLUBLE FIBROUS ARTICLES COMPRISING ACTIVE AGENTS The Procter & Gamble Company (US) 2024-06-12 EP disclosed
CN-117881380-A Soluble solid structure comprising a first polymeric structurant and a second polymeric structurant 宝洁公司 2024-04-12 CN disclosed
US-11925698-B2 Water-soluble fibrous pouch containing prills for hair care THE PROCTER & GAMBLE COMPANY (US) 2024-03-12 US disclosed
EP-1157051-A1 POLYMER DISPERSIONS BASF AKTIENGESELLSCHAFT (DE) 2001-11-28 EP disclosed
WO-2000068162-A1 USE OF POLYSULFATE-FREE PREPARATIONS AS AN ADDITIVE FOR LOAM OR CLAY-BASED CONSTRUCTION MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2000-11-16 WO disclosed
WO-2000040627-A1 POLYMER DISPERSIONS BASF AKTIENGESELLSCHAFT (DE) 2000-07-13 WO disclosed
EP-0384367-A2 Concentrated blends of grafted copolymers of unsaturated-acid esters and ethylene-vinyl ester-copolymers BASF Aktiengesellschaft (DE) 1990-08-29 EP disclosed
US-4906702-A Esters of unsaturated carboxylic acids, preparation of their oil-soluble homo- and copolymers and use thereof as pour point depressants HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-03-06 US disclosed
US-4762946-A POUR POINT DEPRESSANTS, POLYLACTONES, POLYACRYLATES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1988-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11666514-B2 Fibrous structures containing polymer matrix particles with perfume ingredients FSCN1, FLNA, PFN1 TSHR 4800/4885ALDH1A1 1381/4885TDP1 1907/4885
US-11925698-B2 Water-soluble fibrous pouch containing prills for hair care FGF1, CUTA, SPAST TSHR 2705/4885ALDH1A1 423/4885TDP1 2036/4885
US-20200093710-A1 FIBROUS STRUCTURES CONTAINING POLYMER MATRIX PARTICLES WITH PERFUME INGREDIENTS FSCN1, FLNA, PFN1 TSHR 4800/4885ALDH1A1 1381/4885TDP1 1907/4885
US-12029799-B2 Conditioning hair care compositions in the form of dissolvable solid structures SGMS1, CUTA, DGAT1 TSHR 4767/4885ALDH1A1 1717/4885TDP1 3383/4885
US-20070149811-A1 Method for continuously producing alkylamino(meth)acrylamides ACR, MMAB, TET2 TSHR 3088/4885ALDH1A1 74/4885TDP1 758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.