Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | MAX | P61244 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185068 | 0.93 | P2RX7 (0.34) | CTDSP1TRPV1FAAHAURKAMYC | |
| SCHEMBL2808601 | 0.86 | CTDSP1 (0.35) | CTDSP1AURKAMYCMAXP2RX7 | |
| SCHEMBL185912 | 0.85 | AURKA (0.36) | CTDSP1TRPV1FAAHAURKAP2RX7 | |
| SCHEMBL186557 | 0.85 | FAAH (0.37) | CTDSP1TRPV1FAAHAURKAPTK2 | |
| SCHEMBL185942 | 0.84 | FAAH (0.38) | CTDSP1TRPV1FAAHAURKAMYC | |
| SCHEMBL186353 | 0.83 | NAMPT (0.37) | CTDSP1TRPV1FAAHAURKAMYC | |
| SCHEMBL185703 | 0.83 | FAAH (0.37) | CTDSP1TRPV1FAAHAURKAPTK2 | |
| SCHEMBL185974 | 0.83 | CTDSP1 (0.34) | CTDSP1TRPV1FAAHAURKAMYC | |
| SCHEMBL2812345 | 0.83 | POLB (0.43) | CTDSP1KDM4EMEN1KMT2ANAMPT | |
| SCHEMBL2809802 | 0.83 | IDO1 (0.35) | CTDSP1TRPV1AURKAMYCMAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |
| EP-2401256-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097372-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |