Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HBB | P68871 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666267 | 0.79 | MEN1 (0.69) | MEN1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL666266 | 0.79 | MEN1 (0.69) | MEN1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL18585939 | 0.76 | MAPT (0.43) | MEN1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL17595861 | 0.76 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL17595330 | 0.68 | MAPT (0.54) | MEN1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL17595329 | 0.68 | MAPT (0.54) | MEN1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL27289929 | 0.65 | MEN1 (0.69) | MEN1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL666259 | 0.65 | KMT2A (0.69) | MEN1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL666258 | 0.65 | KMT2A (0.69) | MEN1KMT2AMAPK1TDP1LMNA | |
| SCHEMBL5304477 | 0.65 | MEN1 (0.69) | MEN1KMT2AMAPK1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040450-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |