Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.34 |
| ▸ | RELA | Q04206 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615443 | 0.69 | NFKB1 (0.36) | NFKB1NFKB2RELAMEN1MAPK1 | |
| SCHEMBL18586305 | 0.69 | NFKB1 (0.39) | NFKB1NFKB2RELAAPLNR | |
| SCHEMBL20337122 | 0.68 | NFKB1 (0.35) | NFKB1NFKB2RELAMEN1MAPK1 | |
| SCHEMBL6852270 | 0.68 | NFKB1 (0.35) | NFKB1NFKB2RELAMEN1MAPK1 | |
| SCHEMBL29242666 | 0.67 | CA12 (0.33) | NFKB1NFKB2RELAAPLNR | |
| SCHEMBL6180819 | 0.67 | NFKB1 (0.34) | NFKB1NFKB2RELAMEN1MAPK1 | |
| SCHEMBL5812850 | 0.67 | NFKB1 (0.34) | NFKB1NFKB2RELAMEN1MAPK1 | |
| SCHEMBL6183432 | 0.66 | NFKB1 (0.33) | NFKB1NFKB2RELAMEN1MAPK1 | |
| SCHEMBL28540763 | 0.64 | — | — | |
| SCHEMBL7249267 | 0.63 | MEN1 (0.42) | NFKB1NFKB2RELAMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017036436-A1 | PRIMIN DERIVATIVES, METHOD OF PREPARATION THEREOF AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2017-03-09 | — | — | WO | disclosed |