Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 5/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.34 |
| ▸ | RELA | Q04206 | 5/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5812850 | 0.82 | NFKB1 (0.34) | NFKB1NFKB2RELABTKMEN1 | |
| SCHEMBL7615443 | 0.81 | NFKB1 (0.36) | NFKB1NFKB2RELAMEN1MAPK1 | |
| SCHEMBL6183432 | 0.81 | NFKB1 (0.33) | NFKB1NFKB2RELABTKMEN1 | |
| SCHEMBL6852270 | 0.80 | NFKB1 (0.35) | NFKB1NFKB2RELAMEN1MAPK1 | |
| SCHEMBL10363337 | 0.78 | — | — | |
| SCHEMBL1132577 | 0.75 | — | — | |
| SCHEMBL6163687 | 0.74 | CA12 (0.36) | NFKB1NFKB2RELABTK | |
| SCHEMBL6290021 | 0.72 | ALDH1A1 (0.36) | NFKB1NFKB2RELABTKMEN1 | |
| SCHEMBL5227293 | 0.70 | — | — | |
| SCHEMBL4955335 | 0.70 | CACNA1B (0.41) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549613-A1 | SULFONAMIDES HAVING ANTIANGIOGENIC AND ANTICANCER ACTIVITY | Abbott Laboratories (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004033419-A1 | SULFONAMIDES HAVING ANTIANGIOGENIC AND ANTICANCER ACTIVITY | ABBOTT LABORATORIES (US) | 2004-04-22 | — | — | WO | disclosed |