Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 9/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.46 |
| ▸ | PREP | P48147 | 3/20 | 0.45 |
| ▸ | FAP | Q12884 | 2/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798277 | 1.00 | MEN1 (0.53) | MEN1KMT2AACEACE2PREP | |
| SCHEMBL22209510 | 0.90 | ALOX5 (0.46) | MEN1KMT2APREPFAPDPP8 | |
| SCHEMBL22209511 | 0.90 | ALOX5 (0.46) | MEN1KMT2APREPFAPDPP8 | |
| SCHEMBL22209483 | 0.89 | PREP (0.52) | ACEACE2PREPFAPDPP8 | |
| SCHEMBL22811300 | 0.87 | PREP (0.47) | ACE2PREPFAPDPP8DPP9 | |
| SCHEMBL20484700 | 0.85 | MEN1 (0.55) | MEN1KMT2AACEACE2ALDH1A1 | |
| SCHEMBL3171830 | 0.85 | MEN1 (0.55) | MEN1KMT2AACEACE2 | |
| SCHEMBL18586197 | 0.85 | MEN1 (0.55) | MEN1KMT2AACEACE2ALDH1A1 | |
| SCHEMBL20484757 | 0.84 | FAP (0.62) | MEN1KMT2APREPFAP | |
| SCHEMBL18619651 | 0.84 | FAP (0.62) | MEN1KMT2APREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |
| US-10711036-B2 | MALT1 inhibitors and uses thereof | CORNELL UNIVERSITY (US) | 2020-07-14 | — | — | US | disclosed |
| US-20180251489-A1 | MALT1 INHIBITORS AND USES THEREOF | Cornell University Cornell Center for Technology Enterprise & Commercialization (CCTEC) (US) | 2018-09-06 | — | — | US | disclosed |
| EP-3341007-A1 | MALT1 INHIBITORS AND USES THEREOF | Cornell University (US) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017040304-A1 | MALT1 INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2017-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180251489-A1 | MALT1 INHIBITORS AND USES THEREOF | MALT1, BCL3, BCL6 | MEN1 203/4885KMT2A 2424/4885ACE 4250/4885 |
| US-10711036-B2 | MALT1 inhibitors and uses thereof | MALT1, BCL3, BCL6 | MEN1 278/4885KMT2A 2297/4885ACE 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.