Styrene

Styrene

SCHEMBL18587738

C=C(CC(C)=Cc1ccccc1)C(=O)O.C=Cc1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.47
RECQL P46063 1/20 0.45
ALDH1A1 P00352 4/20 0.44
TSHR P16473 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
USP2 O75604 1/20 0.42
ALOX15 P16050 1/20 0.42
MTNR1A P48039 2/20 0.41
MTNR1B P49286 2/20 0.41
HTT P42858 1/20 0.41
GRIK1 P39086 1/20 0.40
GRIK2 Q13002 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
AKR1C1 Q04828 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10352720 0.94 AKR1C3 (0.53) AKR1C3RECQLALDH1A1TSHRSMN1; SMN2
SCHEMBL1789290 0.82 AKR1C3 (0.52) AKR1C3RECQLALDH1A1TSHRSMN1; SMN2
Itaconate SCHEMBL3201278 0.82 ALOX15 (0.57) AKR1C3RECQLALDH1A1TSHRALOX15
Itaconate SCHEMBL9173034 0.80 ALOX15 (0.47) AKR1C3RECQLALDH1A1TSHRALOX15
Itaconate SCHEMBL6572666 0.79 ALOX15 (0.53) AKR1C3RECQLALDH1A1TSHRALOX15
Styrene SCHEMBL238870 0.78 ALDH1A1 (0.52) AKR1C3RECQLALDH1A1TSHRNPC1
Styrene SCHEMBL3102461 0.78 ALDH1A1 (0.47) AKR1C3RECQLALDH1A1TSHRHTT
Styrene SCHEMBL1680068 0.77 ALDH1A1 (0.61) AKR1C3RECQLALDH1A1TSHRSMN1; SMN2
Styrene SCHEMBL76985 0.77 ALDH1A1 (0.61) AKR1C3RECQLALDH1A1TSHRSMN1; SMN2
Styrene SCHEMBL7753037 0.77 ALDH1A1 (0.61) AKR1C3RECQLALDH1A1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10633545-B2 Alcohol-resistant, chemically-strippable floor coating and composition for making same DIVERSEY, INC. (US) 2020-04-28 US claimed
US-20190023907-A1 ALCOHOL-RESISTANT, CHEMICALLY-STRIPPABLE FLOOR COATING AND COMPOSITION FOR MAKING SAME THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2019-01-24 US claimed
EP-3344675-A1 ALCOHOL-RESISTANT, CHEMICALLY-STRIPPABLE FLOOR COATING AND COMPOSITION FOR MAKING SAME Diversey, Inc. (US) 2018-07-11 EP claimed
WO-2017040662-A1 ALCOHOL-RESISTANT, CHEMICALLY-STRIPPABLE FLOOR COATING AND COMPOSITION FOR MAKING SAME DIVERSEY, INC. (US) 2017-03-09 WO claimed
US-10633545-B2 Alcohol-resistant, chemically-strippable floor coating and composition for making same DIVERSEY, INC. (US) 2020-04-28 US disclosed
US-20190023907-A1 ALCOHOL-RESISTANT, CHEMICALLY-STRIPPABLE FLOOR COATING AND COMPOSITION FOR MAKING SAME THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2019-01-24 US disclosed