SCHEMBL1858809

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30516912	0.94	POLB (0.51)	POLBLMNAHSP90AA1HSP90AB1RAB9A
	SCHEMBL1863751	0.90	POLB (0.46)	POLBLMNAHSP90AA1HSP90AB1SOAT1
	SCHEMBL1867068	0.90	POLB (0.46)	POLBLMNAHSP90AA1HSP90AB1SOAT1
	SCHEMBL4138545	0.89	KMT2A (0.48)	POLBLMNAHSP90AA1HSP90AB1SOAT1
	SCHEMBL1863466	0.87	POLB (0.48)	POLBLMNAHSP90AA1HSP90AB1SOAT1
	SCHEMBL5849567	0.84	POLB (0.56)	POLBHSP90AA1HSP90AB1KMT2AMAPK1
	SCHEMBL4124902	0.82	POLB (0.44)	POLBHSP90AA1HSP90AB1HPGDKMT2A
	SCHEMBL26789473	0.81	POLB (0.59)	POLBHSP90AA1HSP90AB1RAB9AHPGD
	SCHEMBL4133128	0.80	PKM (0.56)	KMT2A
	SCHEMBL13678948	0.79	CTSK (0.42)	POLBHSP90AA1HSP90AB1KMT2ACTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.