SCHEMBL185927

SCHEMBL185927

O=C(O)C1=NN(c2ccc(S(=O)(=O)O)cc2)C(=O)C1/N=N/c1ccc(S(=O)(=O)O)cc1.[NaH].[NaH].[NaH]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 9/20 0.51
▸ KMT2A Q03164 9/20 0.51
▸ MAPT P10636 6/20 0.51
▸ CYP1A2 P05177 2/20 0.51
▸ GAA P10253 1/20 0.51
▸ SMN1; SMN2 Q16637 4/20 0.45
▸ ALDH1A1 P00352 4/20 0.45
▸ LMNA P02545 4/20 0.45
▸ NPC1 O15118 4/20 0.45
▸ TDP1 Q9NUW8 2/20 0.45
▸ RAB9A P51151 2/20 0.45
▸ MAPK1 P28482 1/20 0.45
▸ POLB P06746 2/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ ATM Q13315 1/20 0.42
▸ CYP2D6 P10635 2/20 0.40
▸ CYP2C9 P11712 1/20 0.38
▸ PHLPP2 Q6ZVD8 1/20 0.37
▸ CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL839391 0.99 MEN1 (0.52) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL839392 0.99 MEN1 (0.52) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL185928 0.99 MEN1 (0.52) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL29376127 0.98 MEN1 (0.54) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL28836941 0.98 MEN1 (0.51) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL5360382 0.94 MAPT (0.53) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL5355824 0.94 MEN1 (0.58) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL5360387 0.94 MAPT (0.53) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL5355831 0.94 MEN1 (0.58) MEN1KMT2AMAPTCYP1A2GAA
SCHEMBL3282817 0.93 MEN1 (0.47) MEN1KMT2AMAPTCYP1A2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1988009783-A1 POLYMERIC ULTRAVIOLET LIGHT ABSORBERS BIOPOLYMERS LIMITED (AU) 1988-12-15 — — WO claimed
US-8921118-B2 Paper-based microfluidic systems PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2014-12-30 — — US disclosed
EP-1455740-B1 PROCESS FOR PREPARATION OF HAIR TREATMENT COMPOSITION COMPRISING COMPOSITE PARTICLES OF CLAY AND CHARGED ORGANIC MOLECULE UNILEVER PLC (GB) 2012-01-04 — — EP disclosed
EP-2265958-A2 PAPER-BASED MICROFLUIDIC SYSTEMS President and Fellows of Harvard College (US) 2010-12-29 — — EP disclosed
US-7691398-B2 Hair treatment composition comprising composite particles of clay and charged organic molecule UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. (US) 2010-04-06 — — US disclosed
WO-2009121041-A2 PAPER-BASED MICROFLUIDIC SYSTEMS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2009-10-01 — — WO disclosed
US-20080226708-A1 Silicone Vesicles Containing Actives DOW CORNING CORPORATION 2008-09-18 — — US disclosed
EP-1951193-A2 SILICONE VESICLES CONTAINING ACTIVES Dow Corning Corporation (US) 2008-08-06 — — EP disclosed
EP-1317917-B1 Hair colouring composition comprising clay UNILEVER PLC (GB) 2008-01-09 — — EP disclosed
WO-2007053424-A2 SILICONE VESICLES CONTAINING ACTIVES DOW CORNING CORPORATION (US) 2007-05-10 — — WO disclosed
EP-1289381-B1 LOW-STAINING ORANGE FOOD COLORING COMPOSITION PEPSICO INC (US) 2005-11-30 — — EP disclosed
US-20050112074-A1 Hair treatment composition comprising composite particles of clay and charged organic molecule UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2005-05-26 — — US disclosed
US-6737094-B2 FOR PRODUCING BEVERAGE PEPSICO, INC. 2004-05-18 — — US disclosed
US-20030163877-A1 Colouring composition UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-09-04 — — US disclosed
EP-1317917-A1 Hair colouring composition comprising clay UNILEVER PLC (GB) 2003-06-11 — — EP disclosed
US-20020122851-A1 Low-staining orange food coloring composition PEPSICO, INC. 2002-09-05 — — US disclosed
US-5279735-A Hemodialysis membrane cartridge; aqueous percarboxylic acid and azo dye solution MINNTECH CORPORATION (US) 1994-01-18 — — US disclosed
US-5169747-A Anionic dyes and amphoteric polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-08 — — US disclosed
WO-1988009783-A1 POLYMERIC ULTRAVIOLET LIGHT ABSORBERS BIOPOLYMERS LIMITED (AU) 1988-12-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080226708-A1 Silicone Vesicles Containing Actives EXOSC5, EXOSC9, EXOSC10 MEN1 574/4885KMT2A 2234/4885MAPT 2687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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