SCHEMBL185931

SCHEMBL185931

NCc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.62
HSD17B10 Q99714 5/20 0.62
TSHR P16473 5/20 0.62
TDP1 Q9NUW8 4/20 0.62
ALOX12 P18054 3/20 0.62
L3MBTL1 Q9Y468 3/20 0.62
ALOX15 P16050 2/20 0.62
PTGS1 P23219 1/20 0.62
SLC6A2 P23975 1/20 0.62
MAPK1 P28482 1/20 0.62
PTGS2 P35354 1/20 0.62
HTR2B P41595 1/20 0.62
LOXL2 Q9Y4K0 2/20 0.59
CYP3A4 P08684 5/20 0.56
MAPT P10636 4/20 0.56
HTT P42858 2/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2C19 P33261 2/20 0.56
TAAR1 Q96RJ0 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258907 0.90 HRH3 (0.55) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL1459020 0.87 HRH3 (0.52) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL14267973 0.86 LOXL2 (0.59) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL27473567 0.85 ALDH1A1 (0.60) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL28320310 0.83 HRH3 (0.48) ALDH1A1LOXL2MAPTTAAR1MEN1
SCHEMBL28406911 0.81 LOXL2 (0.71) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL8622727 0.80 ALDH1A1 (0.68) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL13308523 0.80 ALDH1A1 (0.68) ALDH1A1HSD17B10TSHRTDP1ALOX12
Biphenyl SCHEMBL27570267 0.80 TAAR1 (0.55) ALDH1A1HSD17B10TSHRTDP1ALOX12
Diphenylamine SCHEMBL28096837 0.79 HSD17B10 (0.71) ALDH1A1HSD17B10TSHRTDP1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108269941-B A kind of production method of the light emitting diode with quantum dots device based on vertical channel SBA-15 confinement 福州大学 2019-08-09 CN claimed
CN-108269941-A A kind of production method of the light emitting diode with quantum dots device based on vertical channel SBA-15 confinements 福州大学 2018-07-10 CN claimed
CN-101128559-A Phosphorescent OLEDs with exciton blocking layer EASTMAN KODAK CO (US) 2008-02-20 CN claimed
CN-104298073-B Colored curable resin composition 东友精细化工有限公司 2019-11-29 CN disclosed
CN-107918247-A COLORED CURABLE RESIN COMPOSITION 住友化学株式会社 2018-04-17 CN disclosed
CN-107132730-A Photosensitive resin composition and application thereof 奇美实业股份有限公司 2017-09-05 CN disclosed
CN-107001299-A Compound and colored curable resin composition 东友精细化工有限公司 2017-08-01 CN disclosed
WO-2017043835-A1 ORGANIC ELECTRONIC DIODE COMPOUND, ORGANIC ELECTRONIC DIODE USING SAME, AND DEVICE THEREFOR 덕산네오룩스 주식회사 2017-03-16 WO disclosed
CN-106019840-A COLORED CURABLE RESIN COMPOSITION 东友精细化工有限公司 2016-10-12 CN disclosed
CN-101128559-B Phosphorescent OLEDs with exciton blocking layer GLOBAL OLED TECHNOLOGY LLC 2014-08-13 CN disclosed
CN-102334172-B Oled device with stabilzed green light-emitting layer GLOBAL OLED TECHNOLOGY LLC 2014-07-09 CN disclosed
CN-1274666-C Composite hole transport material UNIV FUDAN (CN) 2006-09-13 CN disclosed
EP-1669348-A1 NOVEL ANTIFUNGAL AGENT COMPRISING HETEROCYCLIC COMPOUND Eisai Co., Ltd. (JP) 2006-06-14 EP disclosed
CN-1749863-A Charge transmission material containing butadiene structure and its preparing method UNIV TIANJIN (CN) 2006-03-22 CN disclosed
CN-1610198-A Providing an organic vertical cavity laser array device with etched region in dielectric stack EASTMAN KODAK CO (US) 2005-04-27 CN disclosed
CN-1575236-A Imide compounds and optical recording media made by using the same MITSUI CHEMICALS INC OGISO AKI (JP) 2005-02-02 CN disclosed
CN-1458141-A Composite hole transport material UNIV FUDAN (CN) 2003-11-26 CN disclosed
EP-1301464-A1 BIPHENYLCARBOXYLIC ACID AMIDES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS Boehringer Ingelheim Pharma KG (DE) 2003-04-16 EP disclosed
US-20020032238-A1 Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-03-14 US disclosed
WO-2002004403-A1 BIPHENYLCARBOXYLIC ACID AMIDES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-01-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020032238-A1 Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments MTTP, CETP, FABP1 ALDH1A1 190/4885HSD17B10 320/4885TSHR 2039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.