Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18057294 | 0.88 | — | — | |
| SCHEMBL25480538 | 0.75 | PYCR1 (0.31) | — | |
| SCHEMBL23010530 | 0.75 | CA12 (0.38) | ALDH1A1CA12CA2CA9 | |
| SCHEMBL23318152 | 0.75 | ALDH1A1 (0.31) | ALDH1A1HPGDCA12CA2CA9 | |
| SCHEMBL1380469 | 0.71 | ALDH1A1 (0.52) | ALDH1A1HPGDCA12CA2CA9 | |
| SCHEMBL141639 | 0.71 | MEN1 (0.30) | — | |
| SCHEMBL14927150 | 0.70 | CA12 (0.40) | ALDH1A1HPGDCA12CA2CA9 | |
| SCHEMBL8386140 | 0.70 | ALDH1A1 (0.48) | ALDH1A1HPGDCA12CA2CA9 | |
| Hydrochloric Acid SCHEMBL9867770 | 0.69 | ALDH1A1 (0.50) | ALDH1A1HPGDCA12CA2CA9 | |
| SCHEMBL26186692 | 0.69 | SLC6A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170234859-A1 | SPECIFIC TARGETING OF RNA EXPANDED REPEAT SEQUENCES | THE SCRIPPS RESEARCH INSTITUTE | 2017-08-17 | — | — | US | disclosed |
| US-9586944-B2 | Specific targeting of RNA expanded repeat sequences | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-03-07 | — | — | US | disclosed |