SCHEMBL18595029

SCHEMBL18595029

CC(C)c1nc(S)c[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13034847 0.76
SCHEMBL786437 0.73 NOS3 (0.31)
SCHEMBL3322875 0.73
SCHEMBL18827277 0.73
Hydrochloric Acid SCHEMBL28150542 0.71 NOS3 (0.30)
SCHEMBL28079964 0.71 NOS3 (0.30)
Ammonia Solution, Strong SCHEMBL28135320 0.71 NOS3 (0.30)
SCHEMBL17399895 0.71
SCHEMBL4616815 0.71
SCHEMBL19577698 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210188814-A1 PYRIDAZINONE COMPOUNDS AND USES THEREOF CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED (GB) 2021-06-24 US disclosed
US-20210053975-A1 INHIBITORS OF PROTEIN ARGININE DEIMINASES FORWARD THERAPEUTICS, INC. 2021-02-25 US disclosed
US-9637504-B2 Beta-lactamase inhibitors VenatoRx Pharmaceuticals, Inc. (US) 2017-05-02 US disclosed
US-9586902-B2 Histone demethylase inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2017-03-07 US disclosed