SCHEMBL786437

SCHEMBL786437

CC(C)c1c[nH]c(C(C)C)n1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
KDM4E B2RXH2 2/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28150542 0.98 NOS3 (0.30) NOS3NOS1NOS2
Ammonia Solution, Strong SCHEMBL28135320 0.98 NOS3 (0.30) NOS3NOS1NOS2
SCHEMBL28079964 0.98 NOS3 (0.30) NOS3NOS1NOS2
SCHEMBL18827277 0.84
SCHEMBL20998283 0.84
SCHEMBL10363731 0.84
SCHEMBL24792374 0.81
SCHEMBL27831991 0.81
SCHEMBL27850522 0.78 GPR84 (0.32)
SCHEMBL10528473 0.78 SCN10A (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 697 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106893035-B A kind of hydrophobic association modified starch tackifier and preparation method thereof 中国石油化工股份有限公司 2019-08-09 CN claimed
CN-109369859-A Concrete tackifying type viscosity regulator and preparation method thereof 武汉源锦建材科技有限公司 2019-02-22 CN claimed
CN-109223297-A The discoloration of temperature-sensitive three-level is medical defervescence plaster used and preparation method thereof 江西润丰药业有限公司 2019-01-18 CN claimed
CN-108914244-A A kind of preparation method being oriented to synthesis conductive polymer polyanilinc nano fiber using molecular sieve as crystal seed 江苏迪胺新材料科技有限公司 2018-11-30 CN claimed
CN-106496602-A A kind of preparation method of flexible compound hydrogel 山东科技大学 2017-03-15 CN claimed
CN-103436965-B Forbidden photon band is adjustable and present the preparation method of polymer photon crystal of patterning color display JILIN UNIVERSITY (CN) 2016-03-16 CN claimed
CN-103554838-A Epoxy resin with shape memory property and preparation method thereof DONGGUAN JIEYUE SHENGSHI SPORTS GOODS CO LTD 2014-02-05 CN claimed
CN-103436965-A Preparation method of polymer photonic crystals with adjustable photonic band gap and presenting patterned color display UNIV JILIN 2013-12-11 CN claimed
CN-103387512-A Preparation method and intermediate of minocycline CHENGDU CHEMPARTNER CO LTD 2013-11-13 CN claimed
CN-101115679-A Molecular sieve SSZ-70 compositions and synthesis thereof CHEVRON USA INC (US) 2008-01-30 CN claimed
CN-1942560-A Method for preparing small-grain SSZ-32 and application thereof in hydrocarbon conversion method CHEVRON USA INC (US) 2007-04-04 CN claimed
US-20240239797-A1 AKT1 MODULATORS ALTEROME THERAPEUTICS, INC. 2024-07-18 US disclosed
US-20240226114-A1 INHIBITORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. 2024-07-11 US disclosed
US-20240226114-A1 INHIBITORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. 2024-07-11 US disclosed
US-12029708-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2024-07-09 US disclosed
WO-1996016768-A1 PROCESS FOR BONDING WIRES TO OXIDATION-SENSITIVE METAL SUBSTRATES WHICH CAN BE SOLDERED ATOTECH DEUTSCHLAND GMBH (DE) 1996-06-06 WO disclosed
CN-1122607-A Process for producing heavy lubricant oil with low pour point CHEVRON RES & TECH (US) 1996-05-15 CN disclosed
EP-0619333-A2 Process for coating metals ATOTECH Deutschland GmbH (DE) 1994-10-12 EP disclosed
EP-0117825-B1 THE USE OF BISPHENATE SALTS OF TERTIARY AMINES AS LATENT CURING OR ACCELERATING AGENTS FOR EPOXY-PHENOLIC SYSTEMS, METHOD FOR THEIR PREPARATION AND EPOXY-PHENOLIC SYSTEMS CONTAINING THEM MANUFACTURE DE PRODUITS CHIMIQUES PROTEX (FR) 1987-04-01 EP disclosed
EP-0117825-A1 The use of bisphenate salts of tertiary amines as latent curing or accelerating agents for epoxy-phenolic systems, method for their preparation and epoxy-phenolic systems containing them MANUFACTURE DE PRODUITS CHIMIQUES PROTEX (FR) 1984-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239797-A1 AKT1 MODULATORS AKT1S1, AKT1, AKT2 NOS3 3751/4885NOS1 3288/4885NOS2 3784/4885
US-12029708-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER NOS3 1005/4885NOS1 1718/4885NOS2 1964/4885
US-20240226114-A1 INHIBITORS AND USES THEREOF KEAP1, NQO1, NFE2L2 NOS3 1318/4885NOS1 1279/4885NOS2 1075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.