Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26478576 | 0.98 | FAAH (0.43) | FAAHZDHHC7LMNAABCB1ALDH1A1 | |
| SCHEMBL19441279 | 0.93 | FAAH (0.42) | FAAHZDHHC7LMNAABCB1ALDH1A1 | |
| SCHEMBL18595316 | 0.84 | LMNA (0.50) | FAAHZDHHC7LMNACNR1CNR2 | |
| SCHEMBL18558918 | 0.84 | ZDHHC7 (0.47) | FAAHZDHHC7LMNAABCB1CNR1 | |
| SCHEMBL19333632 | 0.84 | LMNA (0.50) | FAAHZDHHC7LMNACNR1CNR2 | |
| SCHEMBL22267806 | 0.83 | ZDHHC7 (0.40) | FAAHZDHHC7LMNAABCB1CNR1 | |
| SCHEMBL5608104 | 0.82 | FAAH (0.58) | FAAHZDHHC7LMNAABCB1ALDH1A1 | |
| SCHEMBL28850975 | 0.82 | FAAH (0.58) | FAAHZDHHC7LMNAABCB1ALDH1A1 | |
| SCHEMBL18595203 | 0.82 | FAAH (0.46) | FAAHZDHHC7LMNAABCB1CNR1 | |
| SCHEMBL18856343 | 0.81 | FAAH (0.47) | FAAHFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586931-B2 | Triazolyl derivatives as Syk inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-03-07 | — | — | US | disclosed |