Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631436 | 0.79 | GRIN2D (0.39) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL21019125 | 0.78 | GRIN2D (0.34) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL27243491 | 0.78 | CHRM2 (0.40) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL8179032 | 0.77 | OPRM1 (0.33) | OPRM1CHRM2OPRD1OPRK1OPRL1 | |
| SCHEMBL19932414 | 0.76 | GRIN2D (0.33) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL648729 | 0.75 | — | — | |
| SCHEMBL648728 | 0.75 | — | — | |
| SCHEMBL23680494 | 0.73 | CRHBP (0.31) | — | |
| SCHEMBL12885045 | 0.73 | OPRM1 (0.38) | OPRM1OPRD1OPRK1OPRL1HSD17B10 | |
| Water SCHEMBL25398465 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9585880-B2 | Cyclic amino compounds for use in the treatment of cardiac disorders | UNIVERSITETET I OSLO (NO) | 2017-03-07 | — | — | US | disclosed |