Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.38 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.38 |
| ▸ | RPS17 | P08708 | 1/20 | 0.38 |
| ▸ | RPSA | P08865 | 1/20 | 0.38 |
| ▸ | RPS2 | P15880 | 1/20 | 0.38 |
| ▸ | RPL35A | P18077 | 1/20 | 0.38 |
| ▸ | RPL7 | P18124 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18653228 | 1.00 | ALDH1A1 (0.50) | ALDH1A1NPC1HTR1AKDM4ECA12 | |
| SCHEMBL18914288 | 1.00 | ALDH1A1 (0.50) | ALDH1A1NPC1HTR1AKDM4ECA12 | |
| SCHEMBL240087 | 0.92 | ALDH1A1 (0.42) | ALDH1A1NPC1KDM4ECA12CA1 | |
| SCHEMBL2367911 | 0.92 | ALDH1A1 (0.42) | ALDH1A1NPC1KDM4ECA12CA1 | |
| SCHEMBL2368747 | 0.92 | ALDH1A1 (0.42) | ALDH1A1NPC1KDM4ECA12CA1 | |
| SCHEMBL18914287 | 0.92 | ALDH1A1 (0.42) | ALDH1A1NPC1KDM4ECA12CA1 | |
| SCHEMBL18925905 | 0.86 | KMT2A (0.40) | ALDH1A1NPC1KDM4ECA12CA1 | |
| SCHEMBL1982239 | 0.85 | CYP19A1 (0.41) | ALDH1A1NPC1KDM4ECA12CA1 | |
| SCHEMBL240466 | 0.81 | ALDH1A1 (0.72) | ALDH1A1NPC1HTR1AKDM4ECA12 | |
| SCHEMBL2368297 | 0.81 | ALDH1A1 (0.72) | ALDH1A1NPC1HTR1AKDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170157104-A1 | Anti-Viral Compounds | ABBVIE INC. (US) | 2017-06-08 | — | — | US | disclosed |
| US-9586978-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2017-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170157104-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | ALDH1A1 2858/4885NPC1 81/4885HTR1A 4719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.