Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.50 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14249636 | 0.90 | PTPN1 (0.61) | PTPN1SLC6A2APPHRH1OPRM1 | |
| SCHEMBL18843328 | 0.79 | PTPN1 (0.50) | PTPN1SLC6A2APPHRH1OPRM1 | |
| SCHEMBL31376243 | 0.79 | HSP90AA1 (0.51) | — | |
| SCHEMBL16244637 | 0.78 | ALOX5 (0.55) | PTPN1SLC6A2APPHRH1OPRM1 | |
| SCHEMBL16244639 | 0.78 | ALOX5 (0.55) | PTPN1SLC6A2APPHRH1OPRM1 | |
| SCHEMBL18597479 | 0.77 | NFKB1 (0.47) | PTPN1SLC6A2APPHRH1OPRM1 | |
| SCHEMBL21710545 | 0.75 | SLC6A2 (0.63) | PTPN1SLC6A2APPHRH1OPRM1 | |
| SCHEMBL23987190 | 0.75 | APP (0.63) | PTPN1SLC6A2APPHRH1OPRM1 | |
| SCHEMBL14249000 | 0.74 | PTPN1 (0.48) | PTPN1SLC6A2APPHRH1OPRM1 | |
| SCHEMBL14248998 | 0.74 | PTPN1 (0.48) | PTPN1SLC6A2APPHRH1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2720693-B1 | CHROMANE-LIKE CYCLIC PRENYLFLAVONOIDS FOR THE MEDICAL INTERVENTION IN NEUROLOGICAL DISORDERS | AIGNER LUDWIG (AT) | 2017-03-08 | — | — | EP | disclosed |