Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1859756 | 0.81 | IDO1 (0.34) | ALDH1A1IDO1POLBMAPT | |
| SCHEMBL1862187 | 0.77 | MAPT (0.36) | ALDH1A1SMN1; SMN2LMNAIDO1HPGD | |
| SCHEMBL28872975 | 0.76 | LTA4H (0.57) | LTA4HALDH1A1SMN1; SMN2LMNAIDO1 | |
| SCHEMBL1859774 | 0.74 | LTA4H (0.55) | LTA4HALDH1A1SMN1; SMN2LMNAIDO1 | |
| SCHEMBL3840431 | 0.74 | LTA4H (0.50) | LTA4HALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1425001 | 0.71 | LTA4H (0.81) | LTA4HALDH1A1SMN1; SMN2LMNAIDO1 | |
| SCHEMBL27884 | 0.71 | LTA4H (0.81) | LTA4HALDH1A1SMN1; SMN2LMNAIDO1 | |
| SCHEMBL25986524 | 0.71 | LTA4H (0.81) | LTA4HALDH1A1SMN1; SMN2LMNAIDO1 | |
| SCHEMBL8306742 | 0.70 | APP (0.42) | SMN1; SMN2NPSR1KDM4EMAPTCYP2D6 | |
| SCHEMBL28131051 | 0.70 | LTA4H (0.60) | LTA4HALDH1A1SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939509-B2 | Partial and full agonists of A1 adenosine receptors | GILEAD SCIENCES, INC. (US) | 2011-05-10 | — | — | US | disclosed |