Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17514697 | 0.84 | ABL1 (0.44) | ABL1ABCB1BCRCYP1A2CYP2D6 | |
| SCHEMBL7703851 | 0.79 | GSTP1 (0.49) | SMN1; SMN2CA1CA2KMT2A | |
| SCHEMBL1646823 | 0.74 | ABL1 (0.50) | ABL1ABCB1BCRSMN1; SMN2CA12 | |
| SCHEMBL456350 | 0.74 | CYP2A6 (0.44) | SMN1; SMN2KDM4ECYP1A2ESR2KMT2A | |
| SCHEMBL4587186 | 0.71 | GCGR (0.43) | ABL1ABCB1BCRCA12CA1 | |
| SCHEMBL8306743 | 0.71 | NPC1 (0.53) | APPABL1ABCB1BCRSMN1; SMN2 | |
| SCHEMBL15063567 | 0.69 | ESR2 (0.47) | APPABL1ABCB1BCRSMN1; SMN2 | |
| SCHEMBL19357316 | 0.69 | CA12 (0.55) | APPABL1ABCB1BCRSMN1; SMN2 | |
| SCHEMBL4820209 | 0.68 | ABL1 (0.47) | APPABL1ABCB1BCRSMN1; SMN2 | |
| SCHEMBL4283008 | 0.68 | HPGDS (0.38) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038992-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-23 | — | — | WO | disclosed |