Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | ALKBH1 | Q13686 | 4/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097308 | 0.77 | ALKBH2 (0.34) | ALKBH2EGLN1ALKBH1HPGDS | |
| SCHEMBL99235 | 0.74 | PRKCI (0.58) | PRKCI | |
| SCHEMBL100600 | 0.71 | — | — | |
| Trifluoroacetic Acid SCHEMBL4097306 | 0.68 | PRKCI (0.50) | ALKBH2EGLN1PRKCI | |
| SCHEMBL16692502 | 0.58 | — | — | |
| SCHEMBL24385169 | 0.58 | HPGDS (0.55) | ALKBH2HPGDS | |
| SCHEMBL28567909 | 0.57 | KMT2A (0.48) | — | |
| Ethylene Glycol SCHEMBL2068360 | 0.57 | MEN1 (0.52) | — | |
| SCHEMBL8871343 | 0.56 | CLK1 (0.48) | — | |
| SCHEMBL3844822 | 0.56 | MEN1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184526-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS JANUS KINASE INHIBITOR | Incyte Holdings Corporation (US) | 2017-06-28 | — | — | EP | disclosed |
| EP-2348023-B9 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2017-03-08 | — | — | EP | disclosed |