Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429636 | 0.80 | — | — | |
| SCHEMBL19258304 | 0.79 | TRPA1 (0.32) | — | |
| SCHEMBL23745122 | 0.77 | ALDH1A1 (0.36) | CRBNALDH1A1TDP1 | |
| SCHEMBL21444599 | 0.75 | CRBN (0.32) | CRBN | |
| SCHEMBL14394470 | 0.73 | — | — | |
| SCHEMBL19656821 | 0.73 | — | — | |
| SCHEMBL18727319 | 0.71 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL19560656 | 0.71 | ALDH1A1 (0.35) | CRBNALDH1A1TDP1 | |
| SCHEMBL19429826 | 0.71 | — | — | |
| SCHEMBL19540807 | 0.71 | MEN1 (0.37) | ALDH1A1TDP1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348023-B9 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2017-03-08 | — | — | EP | disclosed |