Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18129900 | 0.81 | BRD4 (0.34) | BRD4BRD9 | |
| SCHEMBL15728176 | 0.80 | TP53 (0.32) | BRD4BRD9 | |
| SCHEMBL18599285 | 0.80 | GRIN1 (0.34) | GRIN1GRIN2A | |
| SCHEMBL15716772 | 0.79 | GSK3B (0.31) | — | |
| SCHEMBL15716896 | 0.79 | CA2 (0.35) | BRD4BRD9 | |
| SCHEMBL15716758 | 0.78 | PKM (0.33) | BRD4BRD9 | |
| SCHEMBL15728227 | 0.77 | BRD4 (0.30) | BRD4BRD9 | |
| SCHEMBL18598764 | 0.76 | BRD4 (0.32) | BRD4BRD9 | |
| SCHEMBL15716610 | 0.75 | BRD9 (0.32) | BRD4BRD9 | |
| SCHEMBL18599036 | 0.75 | SMN1; SMN2 (0.35) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2920183-B1 | THIENO[3,2-C]PYRIDIN-4(5H)-ONES AS BET INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2017-03-08 | — | — | EP | disclosed |