Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298134 | 1.00 | ALOX5 (0.38) | ALOX5IDO1TDO2TAAR1MAPT | |
| SCHEMBL28296418 | 1.00 | ALOX5 (0.38) | ALOX5IDO1TDO2TAAR1MAPT | |
| Hydrochloric Acid SCHEMBL28923538 | 0.98 | IDO1 (0.39) | ALOX5IDO1TDO2TAAR1MAPT | |
| Hydrochloric Acid SCHEMBL19925908 | 0.98 | IDO1 (0.39) | ALOX5IDO1TDO2TAAR1MAPT | |
| Hydrochloric Acid SCHEMBL19925906 | 0.98 | IDO1 (0.39) | ALOX5IDO1TDO2TAAR1MAPT | |
| Hydrochloric Acid SCHEMBL19925967 | 0.96 | ALOX5 (0.36) | ALOX5IDO1TDO2MAPTSMN1; SMN2 | |
| SCHEMBL4453353 | 0.77 | HTR1A (0.38) | ALOX5IDO1TDO2MAPTSMN1; SMN2 | |
| SCHEMBL11956268 | 0.77 | ALOX5 (0.41) | ALOX5IDO1TDO2MAPTSMN1; SMN2 | |
| SCHEMBL4453350 | 0.77 | HTR1A (0.38) | ALOX5IDO1TDO2MAPTSMN1; SMN2 | |
| SCHEMBL4704141 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843379-B | Substituted ureas and methods of making and using the same | 梅比斯发现公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-109843379-A | Substituted ureas and methods of making and using the same | 梅比斯发现公司 | 2019-06-04 | — | — | CN | disclosed |
| EP-2348023-B9 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2017-03-08 | — | — | EP | disclosed |