Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.37 |
| ▸ | PRKACA | P17612 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MARK3 | P27448 | 1/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19070906 | 0.84 | C1R (0.36) | ROCK2ROCK1PRKACAPDPK1PLK4 | |
| SCHEMBL18848566 | 0.81 | PDPK1 (0.34) | PDPK1ALDH1A1CYP3A4HPGDTSHR | |
| SCHEMBL8404527 | 0.81 | CYP1A2 (0.41) | ROCK2ROCK1PRKACAPDPK1PLK4 | |
| SCHEMBL19044112 | 0.79 | — | — | |
| SCHEMBL12887720 | 0.76 | ALDH1A1 (0.43) | C1RALDH1A1CYP3A4HPGDTSHR | |
| SCHEMBL23206118 | 0.76 | PARP1 (0.39) | ROCK2ROCK1PRKACAPDPK1PLK4 | |
| SCHEMBL5664704 | 0.76 | KDM4E (0.46) | ROCK2ROCK1PRKACAPDPK1PLK4 | |
| SCHEMBL5663599 | 0.76 | ALDH1A1 (0.38) | ROCK2ROCK1PRKACAPDPK1PLK4 | |
| SCHEMBL5657552 | 0.76 | CYP3A4 (0.46) | ROCK2ROCK1PRKACAPDPK1PLK4 | |
| SCHEMBL17041314 | 0.76 | ROCK2 (0.37) | ROCK2ROCK1PRKACAPDPK1PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024031089-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-08 | — | — | WO | disclosed |
| US-20210257559-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-08-19 | — | — | US | disclosed |
| US-10367147-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-07-30 | — | — | US | disclosed |
| US-10312449-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-06-04 | — | — | US | disclosed |
| US-9793487-B2 | — | — | 2017-10-17 | — | — | US | disclosed |
| US-20170186975-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-06-29 | — | — | US | disclosed |
| EP-3138843-A1 | ISOQUINOLINESULFONYL DERIVATIVE AS RHO KINASE INHIBITOR | Medshine Discovery Inc. (CN) | 2017-03-08 | — | — | EP | disclosed |