Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.94 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.94 |
| ▸ | HPGD | P15428 | 3/20 | 0.94 |
| ▸ | TSHR | P16473 | 3/20 | 0.94 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.94 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4941999 | 0.97 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL29413841 | 0.97 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL9029 | 0.97 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL208695 | 0.94 | ALDH1A1 (0.94) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Benzene SCHEMBL22289542 | 0.94 | ALDH1A1 (0.94) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL15485047 | 0.94 | ALDH1A1 (0.94) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Bromide SCHEMBL4288737 | 0.94 | ALDH1A1 (0.94) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL7774409 | 0.94 | ALDH1A1 (0.94) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL7774413 | 0.94 | ALDH1A1 (0.94) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| Water SCHEMBL3981103 | 0.94 | ALDH1A1 (0.94) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118083969-A | Carbon material based on liquid phase deposition and preparation method and application thereof | 玖贰伍碳源科技（天津）有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-114401935-B | Ion channel antagonists/blockers and uses thereof | 上海市东方医院（同济大学附属东方医院） | 2024-04-05 | — | — | CN | disclosed |
| US-20230015875-A1 | Ion Channel Antagonists/Blockers and Uses Thereof | SHANGHAI EAST HOSPITAL (CN) | 2023-01-19 | — | — | US | disclosed |
| CN-114401935-A | Ion channel antagonists/blockers and uses thereof | 上海市东方医院（同济大学附属东方医院） | 2022-04-26 | — | — | CN | disclosed |
| CN-109942435-B | Oxidation coupling high-temperature antioxidant solvent-free preparation method | 江苏飞亚化学工业有限责任公司 | 2021-08-20 | — | — | CN | disclosed |
| WO-2021114313-A1 | ION CHANNEL ANTAGONISTS/BLOCKERS AND USES THEREOF | SHANGHAI EAST HOSPITAL (CN) | 2021-06-17 | — | — | WO | disclosed |
| WO-2020206754-A1 | SOLVENT-FREE PREPARATION METHOD FOR OXIDATIVE COUPLING HIGH-TEMPERATURE ANTIOXIDANT | 江苏飞亚化学工业有限责任公司 | 2020-10-15 | — | — | WO | disclosed |
| US-7935699-B2 | Pyrazole glucokinase activators | HOFFMANN-LA ROCHE INC. (US) | 2011-05-03 | — | — | US | disclosed |
| EP-2261216-A2 | Pyrazoles as glucokinase activators | F. Hoffmann-La Roche AG (CH) | 2010-12-15 | — | — | EP | disclosed |
| EP-2046755-A2 | PYRAZOLES AS GLUCOKINASE ACTIVATORS | F. Hoffmann-Roche AG (CH) | 2009-04-15 | — | — | EP | disclosed |
| US-4092483-A | Intermediates for steroid total synthesis process utilizing asymmetric induction | HOFFMANN-LA ROCHE INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4052436-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1977-10-04 | — | — | US | disclosed |
| US-4026907-A | INTERMEDIATES FOR ALPHA-TOCOPHEROL | HOFFMANN-LA ROCHE INC. (US) | 1977-05-31 | — | — | US | disclosed |
| US-4018799-A | INTERMEDIATES FOR TOCOPHEROL | HOFFMANN-LA ROCHE INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-4011211-A | RING CLOSURE, ACIDS | HOFFMANN-LA ROCHE INC. (US) | 1977-03-08 | — | — | US | disclosed |
| US-4003949-A | 3-KETO-6-(3-ALKOXYPHENYL)-1-HEXENE-6-OL | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-4003919-A | INTERMEDIATES FOR ALPHA-TOCOPHEROL | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-3989841-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3947473-A | (6-HYDROXY-CHROMAN-2-YL) CARBOXYLIC ACID DERIVATIVES | HOFFMAN-LA ROCHE INC. (US) | 1976-03-30 | — | — | US | disclosed |
| US-3932519-A | 7,7A-Dihydro-4-[2-(3-alkoxyphenyl)-2-hydroxyethyl]-7a-alkyl-1, 5(6H)-indandiones,3,4,8,8a-tetrahydro-5-[2-(3-alkoxyphenyl)-2-hydroxyethyl]-8a-alkyl-1,6(7H)-naphthalenediones and processes for the preparation thereof utilizing asymmetric induction | HOFFMANN-LA ROCHE INC. (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230015875-A1 | Ion Channel Antagonists/Blockers and Uses Thereof | CACNA1F, CACNA1S, CACNA1D | ALDH1A1 1001/4885CYP3A4 538/4885HPGD 633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.