SCHEMBL4941999

SCHEMBL4941999

Nc1cccc2ccccc12.Nc1cccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
CYP3A4 P08684 4/20 1.00
TSHR P16473 3/20 1.00
HSD17B10 Q99714 3/20 1.00
HPGD P15428 3/20 1.00
KEAP1 Q14145 2/20 1.00
TDP1 Q9NUW8 3/20 0.67
CYP1A2 P05177 3/20 0.54
LMNA P02545 2/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
CYP2A6 P11509 3/20 0.53
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
KDM4E B2RXH2 2/20 0.52
POLB P06746 2/20 0.52
KMT2A Q03164 2/20 0.52
GLA P06280 1/20 0.52
GAA P10253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9029 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHRHSD17B10HPGD
SCHEMBL29413841 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHRHSD17B10HPGD
SCHEMBL208695 0.97 ALDH1A1 (0.94) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Potassium SCHEMBL11660875 0.97 ALDH1A1 (0.94) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Methane SCHEMBL1860130 0.97 ALDH1A1 (0.94) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Bromide SCHEMBL4288737 0.97 ALDH1A1 (0.94) ALDH1A1CYP3A4TSHRHSD17B10HPGD
SCHEMBL20420881 0.97 ALDH1A1 (0.94) ALDH1A1CYP3A4TSHRHSD17B10HPGD
SCHEMBL9410148 0.97 ALDH1A1 (0.94) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Benzene SCHEMBL22289542 0.97 ALDH1A1 (0.94) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Water SCHEMBL5623206 0.97 ALDH1A1 (0.94) ALDH1A1CYP3A4TSHRHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2950674-A2 IMPROVED AEROSOL FROM TOBACCO Philip Morris Products S.A. (CH) 2015-12-09 EP disclosed
WO-2014118286-A2 IMPROVED AEROSOL FROM TOBACCO PHILIP MORRIS PRODUCTS S.A (CH) 2014-08-07 WO disclosed
US-20080125231-A1 Telescopic Shaft NSK LTD. (JP) 2008-05-29 US disclosed
US-7265080-B2 Rolling bearing, rolling bearing for fuel cell, compressor for fuel cell system and fuel cell system NSK LTD. (JP) 2007-09-04 US disclosed