Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.59 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23198991 | 0.88 | EPHX2 (0.65) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL23199010 | 0.87 | MAPT (0.69) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL8341400 | 0.86 | MAPT (0.69) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL16226054 | 0.85 | EPHX2 (0.57) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL16226388 | 0.85 | MEN1 (0.60) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL6361693 | 0.84 | EPHX2 (0.67) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL16226066 | 0.83 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL30020897 | 0.83 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL16226681 | 0.82 | TTR (0.51) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL16226137 | 0.82 | ALDH1A1 (0.51) | RAB9ANPC1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2301520-B1 | Oxidative dye | HENKEL AG & CO KGAA (DE) | 2017-03-08 | — | — | EP | disclosed |