Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 8/20 | 0.37 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
| ▸ | CTSE | P14091 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.35 |
| ▸ | MME | P08473 | 4/20 | 0.35 |
| ▸ | CPA1 | P15085 | 4/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.34 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15811693 | 1.00 | CYP3A4 (0.37) | CYP3A4SSTR2ACECTSDCTSE | |
| SCHEMBL22419930 | 1.00 | CYP3A4 (0.37) | CYP3A4SSTR2ACECTSDCTSE | |
| SCHEMBL19841574 | 1.00 | CYP3A4 (0.37) | CYP3A4SSTR2ACECTSDCTSE | |
| SCHEMBL20750952 | 0.95 | SSTR2 (0.38) | CYP3A4SSTR2CTSDCTSEBACE1 | |
| SCHEMBL24837336 | 0.94 | SSTR2 (0.38) | CYP3A4SSTR2ACECTSDCTSE | |
| SCHEMBL23894126 | 0.94 | SSTR2 (0.37) | CYP3A4SSTR2ACECTSDCTSE | |
| SCHEMBL24201085 | 0.94 | SSTR2 (0.38) | CYP3A4SSTR2ACECTSDCTSE | |
| SCHEMBL23626306 | 0.94 | CTSD (0.37) | CYP3A4SSTR2ACECTSDCTSE | |
| SCHEMBL21782040 | 0.94 | CTSD (0.37) | CYP3A4SSTR2ACECTSDCTSE | |
| SCHEMBL20749835 | 0.94 | CTSD (0.37) | CYP3A4SSTR2ACECTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357259-A1 | BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-11-09 | — | — | US | disclosed |
| WO-2021050917-A1 | PHOSPHOLIPID ETHER CONJUGATES AS CANCER-TARGETING DRUG VEHICLES | CELLECTAR BIOSCIENCES, INC. (US) | 2021-03-18 | — | — | WO | disclosed |
| EP-2928504-B1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS INC (US) | 2019-02-20 | — | — | EP | disclosed |
| EP-2717916-B1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS INC (US) | 2017-03-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357259-A1 | BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | DOCK11, PAICS, RHOA | CYP3A4 3557/4885SSTR2 2548/4885ACE 4359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.