Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR2 | P30874 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 7/20 | 0.36 |
| ▸ | CTSD | P07339 | 2/20 | 0.35 |
| ▸ | CTSE | P14091 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.34 |
| ▸ | MME | P08473 | 3/20 | 0.34 |
| ▸ | CPA1 | P15085 | 3/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24837336 | 1.00 | SSTR2 (0.38) | SSTR2CYP3A4ACECTSDCTSE | |
| SCHEMBL24837234 | 0.96 | SSTR2 (0.39) | SSTR2CYP3A4ACECTSDCTSE | |
| SCHEMBL24201016 | 0.96 | SSTR2 (0.39) | SSTR2CYP3A4ACECTSDCTSE | |
| SCHEMBL15811693 | 0.94 | CYP3A4 (0.37) | SSTR2CYP3A4ACECTSDCTSE | |
| SCHEMBL19841574 | 0.94 | CYP3A4 (0.37) | SSTR2CYP3A4ACECTSDCTSE | |
| SCHEMBL18602020 | 0.94 | CYP3A4 (0.37) | SSTR2CYP3A4ACECTSDCTSE | |
| SCHEMBL22419930 | 0.94 | CYP3A4 (0.37) | SSTR2CYP3A4ACECTSDCTSE | |
| SCHEMBL19393925 | 0.94 | ACE (0.39) | SSTR2CYP3A4ACEACE2MME | |
| SCHEMBL23106010 | 0.92 | SSTR2 (0.43) | SSTR2CYP3A4ACECTSDCTSE | |
| SCHEMBL23106012 | 0.92 | SSTR2 (0.43) | SSTR2CYP3A4ACECTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388427-B1 | DERIVATIVES OF DOLASTATIN 10 AND AURISTATINS | PF MEDICAMENT (FR) | 2022-01-19 | — | — | EP | disclosed |