Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3839733 | 0.81 | MCL1 (0.53) | — | |
| SCHEMBL18227970 | 0.78 | KDM4E (0.47) | CYP2C9KDM4EHPGDALDH1A1 | |
| Acetic Acid SCHEMBL27918017 | 0.78 | KDM4E (0.51) | KDM4EALDH1A1LMNAHTT | |
| SCHEMBL1090508 | 0.77 | CYP2C9 (0.44) | MAOBCYP2C9KDM4EHPGDALDH1A1 | |
| SCHEMBL6446595 | 0.76 | MCL1 (0.54) | — | |
| SCHEMBL18222929 | 0.76 | CYP2C9 (0.47) | CYP2C9KDM4EHPGDALDH1A1 | |
| SCHEMBL10800028 | 0.76 | ABCG2 (0.54) | KDM4EHPGDALDH1A1LMNAHTT | |
| SCHEMBL10800587 | 0.75 | ABCG2 (0.52) | KDM4EALDH1A1LMNAHTT | |
| SCHEMBL18210532 | 0.74 | KDM4E (0.47) | MAOBCYP2C9KDM4EHPGDLMNA | |
| SCHEMBL26661269 | 0.74 | FAAH (0.48) | CYP2C9KDM4EHPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2665717-B1 | 7-ACYLOXY-CHROMEN-4-ONE DERIVATIVES AND THEIR USE AS SELF-TANNING SUBSTANCES | MERCK PATENT GMBH (DE) | 2015-06-24 | — | — | EP | disclosed |
| EP-1508327-B1 | Use of 5,7-dihydroxy-2-methylchromen-4-on for the care of the skin | MERCK PATENT GMBH (DE) | 2014-05-07 | — | — | EP | disclosed |
| EP-1979337-B1 | CHROMEN-4-ONE DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2011-05-25 | — | — | EP | disclosed |
| EP-1890672-B1 | USE OF CHROMONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2010-06-02 | — | — | EP | disclosed |
| EP-1890672-A1 | USE OF CHROMONE DERIVATIVES | Merck Patent GmbH (DE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006128562-A1 | USE OF CHROMONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2006-12-07 | — | — | WO | disclosed |
| EP-1508327-A1 | Use of chromen-4-one derivatives for the care of skin and hair | MERCK PATENT GmbH (DE) | 2005-02-23 | — | — | EP | disclosed |