Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13203843 | 0.80 | NPY5R (0.47) | HPGDALDH1A1SMN1; SMN2EPHX2ADORA2A | |
| SCHEMBL10113307 | 0.80 | NPY5R (0.47) | HPGDALDH1A1SMN1; SMN2EPHX2ADORA2A | |
| SCHEMBL10114096 | 0.79 | EPHX2 (0.39) | ALDH1A1EPHX2ADORA2AADORA1TSHR | |
| SCHEMBL17842468 | 0.79 | CACNA1G (0.53) | NPC1RAB9ASMN1; SMN2PKMEPHX2 | |
| SCHEMBL2990333 | 0.78 | ADORA2A (0.53) | RAB9ASMN1; SMN2ADORA2AADORA1TSHR | |
| SCHEMBL10353331 | 0.77 | TSHR (0.70) | HPGDSMN1; SMN2PKMTSHRKDM4E | |
| SCHEMBL8321173 | 0.77 | TSHR (0.70) | HPGDSMN1; SMN2PKMTSHRKDM4E | |
| SCHEMBL22501729 | 0.76 | ADORA2A (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2HDAC6 | |
| SCHEMBL18586919 | 0.76 | ADORA2A (0.52) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31606595 | 0.76 | ADORA2A (0.52) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026047-B | Praziquantel and method for producing precursor thereof | 默克专利股份公司 | 2025-06-03 | — | — | CN | disclosed |
| EP-3344605-B1 | METHOD FOR THE PRODUCTION OF PRAZIQUANTEL AND PRECURSORS THEREOF | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | disclosed |
| US-10273213-B2 | Method for the production of praziquantel and precursors thereof | MERCK PATENT GMBH (DE) | 2019-04-30 | — | — | US | disclosed |
| WO-2017036577-A1 | METHOD FOR THE PRODUCTION OF PRAZIQUANTEL AND PRECURSORS THEREOF | MERCK PATENT GMBH (DE) | 2017-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10273213-B2 | Method for the production of praziquantel and precursors thereof | CYP51A1, POR, DHPS | HPGD 199/4885ALDH1A1 519/4885USP2 1893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.