SCHEMBL18607486

SCHEMBL18607486

NCCCCCCCCNC(=O)CCCc1c[nH]c2ccccc12

nearest known ligand 0.78

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.77
KMT2A Q03164 2/20 0.77
MTNR1A P48039 2/20 0.66
IDE P14735 1/20 0.61
CYP1A2 P05177 1/20 0.60
CYP2D6 P10635 1/20 0.60
HPGD P15428 1/20 0.60
CYP2C19 P33261 1/20 0.60
RECQL P46063 1/20 0.60
KDM4E B2RXH2 1/20 0.60
ALDH1A1 P00352 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
MC5R P33032 4/20 0.59
MC3R P41968 4/20 0.59
MC4R P32245 3/20 0.58
NMBR P28336 1/20 0.57
AANAT Q16613 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2824956 0.89 MEN1 (0.83) MEN1KMT2AMTNR1ACYP1A2CYP2C19
SCHEMBL7974250 0.88 MEN1 (0.77) MEN1KMT2AMTNR1AIDECYP1A2
SCHEMBL18607543 0.88 MEN1 (0.77) MEN1KMT2AMTNR1AIDECYP1A2
SCHEMBL9797755 0.85 LMNA (0.63) MEN1KMT2AALDH1A1AANAT
SCHEMBL19051489 0.85 MEN1 (0.80) MEN1KMT2AMTNR1ACYP1A2CYP2C19
SCHEMBL23417988 0.85 MEN1 (0.68) MEN1KMT2AMTNR1AIDECYP1A2
SCHEMBL23417825 0.84 MEN1 (0.71) MEN1KMT2AMTNR1AIDECYP1A2
SCHEMBL5578012 0.84 MEN1 (0.83) MEN1KMT2AMTNR1AIDECYP1A2
SCHEMBL1233177 0.83 MEN1 (0.81) MEN1KMT2AMTNR1ACYP1A2CYP2C19
SCHEMBL6646410 0.83 MTNR1A (0.88) MEN1KMT2AMTNR1AIDECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017038926-A1 ANTIBODY SUBJECTED TO FLUORESCENT LABELING USING NUCLEOTIDE BINDING SITE (NBS) OF ANTIBODY 国立大学法人東京工業大学 2017-03-09 WO disclosed