Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 5/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.47 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | NEK4 | P51957 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18610020 | 0.86 | ROCK1 (0.49) | ROCK1ROCK2JAK2JAK3JAK1 | |
| Hydrochloric Acid SCHEMBL18584458 | 0.86 | ROCK1 (0.49) | ROCK1ROCK2JAK2JAK3JAK1 | |
| SCHEMBL18609851 | 0.79 | ROCK1 (0.42) | ROCK1ROCK2JAK2MAPK1AURKB | |
| Hydrochloric Acid SCHEMBL18584862 | 0.79 | ROCK1 (0.41) | ROCK1ROCK2JAK2MAPK1AURKB | |
| SCHEMBL18609822 | 0.78 | KDM1A (0.38) | ROCK1ROCK2ACACACASR | |
| SCHEMBL18609660 | 0.78 | ROCK1 (0.41) | ROCK1ROCK2JAK2MAPK1RPS6KB1 | |
| SCHEMBL18609917 | 0.78 | ROCK1 (0.44) | ROCK1ROCK2JAK3MAPK1RPS6KB1 | |
| SCHEMBL18609246 | 0.77 | CASR (0.40) | ROCK1ROCK2MAPK1RPS6KB1MAP4K4 | |
| Hydrochloric Acid SCHEMBL18584811 | 0.77 | ROCK1 (0.43) | ROCK1ROCK2JAK3MAPK1RPS6KB1 | |
| SCHEMBL18609820 | 0.76 | FGFR2 (0.52) | MAPK1CDK2CLK4KDRCASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017037616-A1 | ARYLALKYLAMINE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2017-03-09 | — | — | WO | disclosed |