Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 9/20 | 0.52 |
| ▸ | FGFR3 | P22607 | 9/20 | 0.52 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | TTK | P33981 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609806 | 0.85 | PFKFB3 (0.47) | FGFR2FGFR3FGFR4GRM2PFKFB3 | |
| SCHEMBL18609822 | 0.81 | KDM1A (0.38) | PFKFB3CASRMAPTATM | |
| SCHEMBL18609939 | 0.79 | ACACA (0.40) | FGFR2FGFR3FGFR4PFKFB3KIT | |
| SCHEMBL16548183 | 0.78 | PFKFB3 (0.44) | FGFR2FGFR3FGFR4PFKFB3KIT | |
| SCHEMBL18609917 | 0.77 | ROCK1 (0.44) | PFKFB3CDK2CASRMAPTATM | |
| Hydrochloric Acid SCHEMBL17939872 | 0.77 | PFKFB3 (0.44) | FGFR2FGFR3FGFR4PFKFB3FGFR1 | |
| SCHEMBL18609659 | 0.76 | ROCK1 (0.47) | CDK2KDRCASRMAPK1CLK4 | |
| Hydrochloric Acid SCHEMBL18584811 | 0.76 | ROCK1 (0.43) | PFKFB3CDK2CASRMAPTATM | |
| SCHEMBL18609246 | 0.76 | CASR (0.40) | PFKFB3CDK2CASRMAPTATM | |
| SCHEMBL18610315 | 0.74 | ROCK1 (0.42) | PFKFB3CDK2CASRMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017037616-A1 | ARYLALKYLAMINE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2017-03-09 | — | — | WO | disclosed |