Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | CASR | P41180 | 5/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609846 | 0.85 | PFKFB3 (0.42) | PFKFB3FAAHCASRRIPK1HSP90AA1 | |
| SCHEMBL18609855 | 0.85 | PFKFB3 (0.40) | KDM1APFKFB3FAAHCASRHSD11B1 | |
| SCHEMBL18609820 | 0.81 | FGFR2 (0.52) | PFKFB3CASRMAPTATM | |
| SCHEMBL18609917 | 0.79 | ROCK1 (0.44) | PFKFB3CASRROCK2ROCK1MAPT | |
| SCHEMBL18609659 | 0.78 | ROCK1 (0.47) | ACACACASRROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL18584811 | 0.78 | ROCK1 (0.43) | PFKFB3CASRROCK2ROCK1MAPT | |
| SCHEMBL18609246 | 0.78 | CASR (0.40) | PFKFB3ACACACASRROCK2ROCK1 | |
| SCHEMBL18609939 | 0.77 | ACACA (0.40) | PFKFB3ACACACASRROCK2ROCK1 | |
| SCHEMBL18610315 | 0.76 | ROCK1 (0.42) | PFKFB3CASRROCK2ROCK1MAPT | |
| SCHEMBL18609805 | 0.75 | LTB4R (0.40) | PFKFB3CASRROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017037616-A1 | ARYLALKYLAMINE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2017-03-09 | — | — | WO | disclosed |