Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 5/20 | 0.42 |
| ▸ | CASR | P41180 | 6/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609822 | 0.85 | KDM1A (0.38) | PFKFB3CASRSLC6A2SLC6A4RIPK1 | |
| SCHEMBL18609855 | 0.84 | PFKFB3 (0.40) | PFKFB3CASRSLC6A2SLC6A4CYP3A4 | |
| SCHEMBL16548307 | 0.81 | MEN1 (0.47) | PFKFB3CASRSLC6A2SLC6A4CYP3A4 | |
| Hydrochloric Acid SCHEMBL17939978 | 0.80 | MEN1 (0.46) | PFKFB3CASRSLC6A2SLC6A4CYP3A4 | |
| SCHEMBL17945540 | 0.79 | CASR (0.45) | PFKFB3CASRSLC6A2SLC6A4CYP3A4 | |
| SCHEMBL16548293 | 0.79 | CASR (0.45) | PFKFB3CASRSLC6A2SLC6A4CYP3A4 | |
| SCHEMBL18215340 | 0.79 | CASR (0.45) | PFKFB3CASRSLC6A2SLC6A4CYP3A4 | |
| SCHEMBL18609806 | 0.78 | PFKFB3 (0.47) | PFKFB3CASR | |
| Hydrochloric Acid SCHEMBL17939846 | 0.78 | CASR (0.45) | PFKFB3CASRSLC6A2SLC6A4CYP3A4 | |
| Hydrochloric Acid SCHEMBL17939817 | 0.78 | CASR (0.44) | PFKFB3CASRSLC6A2SLC6A4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017037616-A1 | ARYLALKYLAMINE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2017-03-09 | — | — | WO | disclosed |